脓毒症评分研究进展

Research progress of sepsis score

脓毒症是机体对感染的反应失调而引起的危及生命的器官功能障碍。因其发病率高,病情进展迅速,病死率高,一直被强烈关注。脓毒症的发病机制目前尚不明确,脓毒症定义从1992年脓毒症1.0解释为宿主对感染的全身炎症反应到2016年脓毒症3.0变为对感染的反应失调而引起的危及生命的器官功能障碍,人们对脓毒症正在逐步了解,对脓毒症的诊断和预后评估的评分系统也在进一步完善。本文主要对脓毒症相关评分系统及临床价值进行综述。

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection.Because of its high incidence,rapid disease progression,and high mortality,sepsis has been attracting much attention.The pathogenesis of sepsis is not yet clear,and the definition has changed from sepsis 1.0 in 1992 of life-threatening organ dysfunction caused by the host systemic inflammatory response to infection to sepsis 3.0 in 2016 of dysregulation in response to infection.Sepsis is being gradually understood,and the scoring system for the diagnosis and prognostic evaluation of sepsis is also being further improved.This review focuses on sepsis-related scoring systems and their clinical values.