摘要
从骨组织工程支架孔隙形状、孔径大小、孔隙率、表面粗糙度、连接通路5方面对支架孔的微观结构的研究现状进行了综述。发现梯度结构的支架孔隙形状更接近天然骨,粗糙的表面可以改善细胞的黏附和增殖,非正交连接通路的内部结构可以为后期骨再生提供一个动态的生长空间。
This paper reviewed the research status of the microstructure of scaffold pores from five aspects,including the pore shape,pore size,porosity,surface roughness,and connection pathways of bone tissue engineering scaffolds.The pore shape of the scaffold with a gradient structure was found to be closer to those of the natural bone.The rough surface can improve the cell adhesion and proliferation of the scaffolds,and the internal structure of the non⁃orthogonal connec⁃tion pathway can provide a dynamic growth space for later bone regeneration.
作者
张伟蒙
汪杰
胡晶
ZHANG Weimeng;WANG Jie;HU Jing(School of Chemistry and Materials Engineering,Beijing Technology and Business University,Beijing 100048,China)
出处
《中国塑料》
CAS
CSCD
北大核心
2022年第12期155-166,共12页
China Plastics
关键词
三维打印
骨组织
支架
结构
性能
three dimensional printing
bone tissue
scaffold
structure
property