清中汤加减治疗慢性胃炎湿热中阻型患者的效果观察

Effect Observation of Modified Qingzhong Decoction in Treatment of Chronic Gastritis Patients with Syndrome of Damp-Heat Blocking Middle Jiao

目的:观察清中汤加减治疗慢性胃炎湿热中阻型患者的临床效果。方法:选取2018年5月-2021年8月赣州市南康区曹春萌诊所收治的慢性胃炎湿热中阻型患者70例为观察对象,以双盲抽签法分为对照组与观察组,各35例。对照组给予常规西药治疗,观察组给予清中汤加减治疗,比较两组患者症状缓解时间、治疗总有效率、中医证候积分及不良反应发生率。结果:观察组患者胃黏膜恢复时间、反酸缓解时间、饱胀缓解时间、腹痛消失时间低于对照组,差异有统计学意义(P<0.05);观察组总有效率高于对照组,差异有统计学意义(P<0.05);治疗后,观察组腹痛、反酸、饱胀评分低于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论:慢性胃炎湿热中阻型患者给予清中汤加减治疗效果较为显著,可及时改善患者症状,缩短临床症状时间,调节胃肠功能,消除体内炎性反应,对机体的不良反应较少,安全性较高。

Objective:To observe the clinical effect of modified Qingzhong Decoction in the treatment of patients with chronic gastritis with syndrome of damp-heat blocking middle jiao.Methods:A total of 70 patients with chronic gastritis with syndrome of damp-heat blocking middle jiao admitted to Cao Chun-meng Clinic of Nankang District of Ganzhou City from May 2018 to August 2021 were selected as the observation subjects,and they were divided into control group and observation group by double-blind lot method,with 35 cases in each group.The control group was given routine western medicine treatment,and the observation group was treated with modified Qingzhong Decoction.The symptom relief time,total effective rate of treatment,TCM symptom scores and incidence of adverse reactions were compared between the two groups.Results:The gastric mucosa recovery time,acid regurgitation relief time,fullness relief time,abdominal pain disappearance time in the observation group were lower than those in the control group,with statistically significant difference(P<0.05).The total effective rate of treatment in the observation group was higher than that in the control group,with statistically significant difference(P<0.05).After treatment,the scores of abdominal pain,acid regurgitation and fullness in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:The treatment effect of modified Qingzhong Decoction in patients with chronic gastritis with syndrome of damp-heat blocking middle jiao is more significant,which can improve the symptoms of patients in time,shorten the time of clinical symptoms,regulate gastrointestinal function,eliminate inflammation in the body,and reduce the adverse reaction in the body,with high safety.