基于医药协同安全用药策略“临床用药告知”的研究与实践

Research and practice of“clinical medication notice”,a medication safety strategy based on medicine and medication synergy

在药物治疗仍然占据绝对主导地位的今天,用药安全问题受到医药工作者及人民大众的广泛关注。人民日益增长的用药安全需求与专业人才短缺、确保用药安全的方法和手段不够健全的矛盾逐渐突现。为了更好地实现药物治疗的有效性和安全性,基于医药协同的学术思想创新性地提出以“临床用药告知”为桥梁的安全用药策略,并通过临床实践证明这一策略是快速提升安全用药水平的有效手段。本文系统介绍了临床用药告知的理论体系、内容和方法。“临床用药告知”的提出,旨在解决医药分割造成的临床用药安全隐患。其理论体系是基于中医药与用药安全密切相关的内容,切入药和医两个维度,整合中药药性理论和现代药物警戒思想而构成的。“临床用药告知”不仅仅是对药物使用的指导,而是以患者为中心,在医药融通的视角下,结合疾病认知、药物特性、服药方法、安全信息、生活调适与用药监护一体化的安全用药策略。经过数十年来的临床实践,“临床用药告知”的方法和路径逐渐成熟,并已形成了特色临床规范。对于提升用药依从性、降低药物不良事件、促进合理用药、保障临床疗效起到积极作用。

Medication safety has been drawing much attention from medical staff and the public as drug therapy still prevails nowadays.However,the increasing demand of medication safety failed to be met due to problems such as the shortage of specialists and insufficient approaches.To further achieve the efficacy and safety of drug therapy,a medication safety strategy of“clinical medication notice”mechanism was proposed innovatively based on the academic idea of medicine and medication synergy.Clinical practice has proved it effective to improve medication safety.The present study systematically introduces the medication safety strategy,including its theories,contents,and method.Specifically,the strategy aims to bridge the gap between clinical medicine and medication administration.With its roots deep in medicine and medication in traditional Chinese medicine(TCM),it integrates the TCM theory of properties with modern pharmacovigilance.In addition to guiding medication,the strategy combines knowledge of diseases,characteristics of drugs,administration,safety information,lifestyle modification,and medication monitoring from the prospective of medicine and medication synergy with patients as the center.After decades of clinical practice,the pathways and approaches of clinical medication notice have been gradually improved with clinical standardization formed,which will improve medication compliance,reduce adverse drug events,promote rational medication,and ensue clinical efficacy.