黄芪建中汤合理中汤联合西药治疗脾胃虚寒型胃痛患者的效果

Effects of Huangqi Jianzhong decoction and Lizhong decoction combined with western medicine on stomachache of spleen-stomach deficiency cold type

目的:观察黄芪建中汤合理中汤联合西药治疗脾胃虚寒型胃痛患者的效果。方法:选取2019年3月至2021年3月该院收治的78例脾胃虚寒型胃痛患者进行前瞻性研究,按病历号奇偶数分为对照组和观察组各39例。对照组采用常规西药治疗,观察组在对照组基础上采用黄芪建中汤合理中汤治疗,比较两组治疗前后中医证候积分,以及临床疗效、症状缓解时间和不良反应发生率。结果:治疗后,两组胃脘隐痛、畏寒肢冷、胃脘胀满、神疲肢倦等中医证候积分均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05);观察组治疗总有效率为97.44%(38/39),高于对照组的79.49%(31/39),差异有统计学意义(P<0.05);观察组胃脘隐痛、胃脘胀满、嗳气泛酸、神疲肢倦等症状缓解时间均短于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:黄芪建中汤合理中汤联合常规西药治疗脾胃虚寒型胃痛患者可提高治疗总有效率,缩短症状缓解时间,降低中医证候积分,效果优于单纯西药治疗。

Objective: To observe effects of Huangqi Jianzhong decoction and Lizhong decoction combined with western medicine on stomachache of spleen-stomach deficiency cold type. Methods: From March 2019 to March 2021, 78 patients with stomachache of spleen-stomach deficiency cold type admitted to the hospital were selected for the prospective study. According to the odd and even number of medical records, they were divided into control group and observation group, 39 cases in each group. The control group was treated with conventional western medicine, while the observation group was treated with Huangqi Jianzhong decoction and Lizhong decoction on the basis of that of the control group. The scores of TCM syndromes before and after the treatment, the curative effects, the clinical symptom remission time, and the incidence of adverse reactions were compared between the two groups. Results: After the treatment, the scores of TCM syndromes such as epigastric vague pain, chilliness and cold limbs, epigastric fullness, mental fatigue and limb fatigue in the two groups were lower than those before the treatment, those in the observation group were lower than the control group, and the differences were statistically significant(P<0.05). The total effective rate of treatment in the observation group was 97.44%(38/39), which was higher than 79.49%(31/39) in the control group, and the difference was statistically significant(P<0.05). The remission time of symptoms such as epigastric vague pain epigastric fullness, belching and pantothenic acid, and mental fatigue in the observation group was shorter than that in the control group, and the difference was statistically significant(P<0.05). However, there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05). Conclusions: Huangqi Jianzhong decoction and Lizhong decoction combined with conventional western medicine can improve the total effective rate of treatment, shorten the remission time of clinical symptoms and reduce the score of TCM syndromes in the patients with stomachache of spleen and stomach deficiency cold type. Moreover, it is superior to single conventional western medicine treatment.