硫酸镁与硝苯地平联合心理治疗对妊高症患者的效果

Effect of magnesium sulfate and nifedipine combined with psychotherapy on patients with pregnancy induced hypertension

目的探讨硫酸镁与硝苯地平联合心理治疗对妊高症患者情绪、心理及睡眠质量的影响。方法遴选时段2020年1月~2021年1月内500例妊高症患者,根据随机数字表法分2组,接受硫酸镁与硝苯地平治疗治疗250例(对照组),对照组基础上联合心理治疗250例(观察组)。对比指标:临床总疗效、患者血压控制情况、心理状态、睡眠质量评分、心理弹性评分。结果观察组患者用药总疗效较对照组明显高(P<0.05);两组治疗前血压水平比较,均无统计学差异(P>0.05),观察组治疗后收缩压、舒张压均显著低于对照组(P<0.05);两组治疗前焦虑、抑郁评分比较,无统计学差异(P>0.05),观察组治疗后焦虑自评量表(Self-Rating Anxiety Scale,SAS)评分、抑郁自评量表(Self-rating depression scale,SDS)评分较对照组更低(P<0.05);两组治疗干预前匹兹堡睡眠质量指数(Pittsburgh Sleep Quality Index,PSQI)评分比较(P>0.05),观察组干预后PSQI评分显著低于对照组(P<0.05);两组治疗前心理弹性评分无差异(P>0.05),两组治疗后较同组治疗前心理弹性量表(Connor-Davidson resilience scale,CD-RISC)评分明显升高,且观察组较对照组升高幅度更明显(P<0.05)。结论硫酸镁与硝苯地平配合心理治疗不仅有利于患者血压水平的稳定控制,同时有效改善患者负面情绪及增强心理弹性,提高睡眠质量,从而实现改善母婴结局、提高患者生活质量的目的。

Objective To explore the effects of magnesium sulfate and nifedipine combined with psychotherapy on emotion,psychology and sleep quality in patients with pregnancy induced hypertension(PIH).Methods During the selection period from January 2020 to January 2021,500 patients with pregnancy-induced hypertension were divided into 2 groups according to the random number table method,and 250 cases received magnesium sulfate and nifedipine treatment(control group),and the control group combined on the basis of Psychological treatment of 250 cases(observation group).Comparative indicators:total clinical efficacy,blood pressure control,psychological state,sleep quality score,and psychological resilience score.Results The total curative effect of the observation group was significantly higher than that of the control group(P<0.05).There was no significant difference in blood pressure between the two groups before treatment(P>0.05).The systolic and diastolic blood pressure in the observation group were significantly lower than those in the control group(P<0.05).The scores of self rating Anxiety Scale(SAS)and self rating Depression Scale(SDS)in the observation group were lower than those in the control group(P<0.05).Pittsburgh sleep quality index(Pittsburgh)before treatment intervention Sleep Quality The PSQI score of the observation group was significantly lower than that of the control group(P<0.05).The score of psychological elasticity before treatment in the two groups was not different(P>0.05).After treatment,the score of Connor Davidson Resilience Scale(cd-risc)in the two groups was significantly higher than that in the same group,and the increase in the observation group was more obvious than that in the control group(P<0.05).Conclusion The combined application of magnesium sulfate and nifedipine in the treatment of patients with PIH,combined with psychopsychotherapy,is not only conducive to the stable control of blood pressure level,but also effective in patients’negative emotion,enhancing psychological elasticity and improving sleep quality,so as to improve the situation of mother and child and improve the quality of life of patients.