桦褐孔菌小分子化合物化学成分及其药用价值的研究进展

Research Progress on Small Molecule Chemical Components and Pharmacological Values of Inonotus obliquus

桦褐孔菌Inonotus obliquus (Ach.ex Pers.) Pilát是一种寄生在桦树上的药用真菌,含有多种生物活性成分,在抗氧化、抗菌、抗病毒、提高免疫力及治疗癌症等方面具有显著功效,这些化学成分作为医药先导物受到了广泛关注。总结了目前从桦褐孔菌中分离并发现的萜类、甾体、酚类等小分子化合物,共计130种。通过对桦褐孔菌小分子化合物活性成分的结构介绍以及药理作用方面相关研究的总结,为桦褐孔菌药用活性成分的开发及研究提供参考。

Inonotus obliquus(Ach.ex Pers.) Pilát is a kind of medicinal macrofungus which parasitizes in birch trees.It contains a variety of biologically active constituents with significant effects of antioxidant,antibacterial,antiviral,immune enhancement and treatment of cancer.These chemical constituents have received extensive attention as pharmaceutical precursor.Herein,we summarize terpenoids,steroids,phenols small molecule compounds discovered from a total of 130 species of I.obliquus up to now.Through the introduction of the structure and pharmacological activities of chemical constituents of I.obliquus,it will provide the reference for the development and research on the medicinal active constituents of I.obliquus.