两种手术方法对声带白斑患者的治疗效果

Treatment Effect of Two Kinds of Surgical Methods in Patients with Vocal Cord Leukoplakia

目的探讨两种手术方法对声带白斑患者嗓音功能、声带功能、复发率的影响,为临床上选取手术方法提供参考。方法选取濮阳市油田总医院2018年1月至2022年1月收治的200例声带白斑患者为研究对象,根据手术方式分为研究组(n=125)和对照组(n=75)。对照组接受支撑喉镜下剥脱术治疗,研究组接受CO_(2)激光术治疗。观察比较两组患者嗓音功能、声带功能以及术后复发情况。结果研究组有效率(100.00%)高于对照组(93.33%)(P<0.05)。术后,两组患者振幅微扰、基频微扰以及噪/谐比均下降,且研究组低于对照组(P<0.05)。术后,两组患者声带振动对称性和声带黏膜波评分均下降,且研究组低于对照组(P<0.05)。研究组患者随访3、6个月时复发率(0.80%、1.60%)均低于对照组(5.33%、12.00%)(P<0.05)。结论相较于支撑喉镜下剥脱术,CO_(2)激光术对于声带白斑患者的疗效更好,能更好改善患者的嗓音功能和声带功能,降低术后复发风险。

Objective To investigate the effect of two kinds of surgical methods on voice function,vocal cord function and recurrence rate in patients with vocal cord leukoplakia,and to provide reference for clinical application.Methods Two hundred patients with vocal cord leukoplakia in Puyang Oilfield General Hospital from January 2018 to January 2022 were enrolled and divided into control group(n=75)and study group(n=125)according to surgical methods.Control group received self-retaining laryngoscope assisted dissection,while study group received CO_(2)laser.Then comparison was conducted on the voice function,vocal cord function and recurrence rate.Results The overall efficacy rate in study group(100.00%)was higher than that(93.33%)in control group(P<0.05).The shimmer amplitude perturbation,jitter frequency perturbation and noise to harmonic ratio were decreased in both groups after treatment,and the values of above three parameters in study group were lower than those in control group(P<0.05).Vocal cord vibration symmetry and vocal cord mucosal wave score in both groups were decreased in both groups after treatment,and the scores in study group were lower than those in control group(P<0.05).Recurrence rate of patients in the study group at 3 months and 6 months of follow-up in study group(0.80%,1.60%)were lower than those(5.33%,12.00%)in control group(P<0.05).Conclusion Compared with the stripping operation under the supporting laryngoscope,CO_(2)laser is more effective for patients with vocal cord leukoplakia,which can better improve the voice function and vocal cord function of patients and reduce the risk of postoperative recurrence.