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分析慢性心力衰竭患者实施β受体阻滞剂联合他汀类药物的效果

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摘要 目的浅析β受体阻滞剂联合他汀类药物治疗慢性心力衰竭(简称心衰)的临床效果。方法选取2019年3月至2020年3月济南市长清区中医医院收入的78例慢性心衰患者的临床资料进行回顾性分析,依据治疗方式的不同分为对照组(39例,常规抗心衰药物治疗)与试验组(39例,β受体阻滞剂联合他汀类药物治疗)。就患者治疗效果、心功能、炎症因子、N端脑钠肽前体(NF-proBNP)、血清基质金属蛋白酶-2(MMP-2)及血清基质金属蛋白酶-9(MMP-9)指标进行分析。结果与对照组相比,试验组患者的临床效果显著提升(P<0.05)。治疗后,两组患者的心功能各项指标、NF-proBNP、高敏C反应蛋白(hs-CRP)、白介素-6(IL-6)、C反应蛋白(CRP)、MMP-2、MMP-9指标均降低,且除了NF-proBNP两组治疗后相比差异无统计学意义(P>0.05)以外,上述其他指标试验组更低于对照组,差异有统计学意义(P<0.05)。结论β受体阻滞剂+他汀类药物治疗慢性心衰患者,能显著改善其心功能,提升治疗效果,降低相关炎症因子水平。
出处 《大医生》 2022年第24期99-101,共3页 Doctor
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