体育运动对抑郁症的干预研究

Research Progress on the Neuromechanism of Exercise Interventions for Depression

抑郁症(depression)是一种十分普遍的神经精神疾病,它是先天遗传因素和后天环境因素共同作用的结果,并有其复杂的神经生理和病理机制。抑郁症患者的健康水平和生存质量普遍较低,严重抑郁患者还会有自杀的倾向。目前,药物疗法依然是抑郁症治疗的主要手段,但是长期服药不仅会带来严重的副作用,还会加重患者经济负担,降低治疗依从性。本研究在综述抑郁症的各种诱发因素的基础上,重点探讨了体育运动对抑郁症的干预作用,以及运动干预抑郁症的相关机制,同时还归纳了针对抑郁症的运动干预方案,以期为抑郁症的预防与治疗提供可供参考的方法。

Depression is a very common neuropsychiatric disease. It is the result of the combination of congenital genetic factors and environmental factors, and has complex neurophysiological and pathological mechanisms. Life qualities of depressed patients are generally low, as severely depressed patients even have a tendency to commit suicide.At present, drug therapy is still the main means of depression treatment, but long-term medication will not only bring serious side effects, but also increase the economic burden of patients and reduce treatment compliance. In order to provide reference for the prevention and treatment of depression, this review focused on the effect of exercise intervention on depression and the relevant mechanisms, based on the introduction of the various inducing factors of depression.In the meanwhile, targeted exercise intervention protocols have also been summarized.