腹腔镜剔除术治疗子宫肌瘤的疗效观察

Observation of the curative effect of laparoscopic culling in the treatment of uterine fibroids

目的 分析腹腔镜剔除术治疗子宫肌瘤的临床效果。方法 选取200例子宫肌瘤患者,根据治疗方案不同分为研究组(采用腹腔镜剔除术治疗)和对照组(采用传统手术治疗),每组100例。比较两组治疗效果。结果 研究组总有效率97.00%高于对照组的55.00%,差异有统计学意义(P<0.05)。研究组手术时间、术中出血量、术后排气时间、下床时间、住院时间、疼痛评分分别为(67.95±5.30)min、(57.24±3.28)ml、(11.53±2.64)h、(21.10±3.25)h、(5.23±1.35)d、(3.10±1.24)分,对照组为(114.23±6.23)min、(98.30±6.24)ml、(32.48±4.90)h、(53.12±5.13)h、(10.43±4.63)d、(9.24±2.64)分。研究组手术时间、术后排气时间、下床时间、住院时间均短于对照组,术中出血量少于对照组,疼痛评分低于对照组,差异有统计学意义(P<0.05)。研究组并发症发生率低于对照组,差异有统计学意义(P<0.05)。研究组患者的去甲肾上腺素(NE)、血管紧张素II(Ang-Ⅱ)及内皮素-1(ET-1)指标低于对照组,差异有统计学意义(P<0.05)。结论 子宫肌瘤采用腹腔镜剔除术的治疗效果相比传统手术治疗,临床疗效显著,术后康复速度快,并发症发生率低。

Objective To analyze the effect of laparoscopic culling in the treatment of uterine fibroids. Methods 200patients with uterine fibroids were selected and divided into two groups according to different treatment plans: the study group(treated with laparoscopic culling) and the control group(treated with traditional surgery), with 100 cases in each group. The therapeutic effect of the two groups was compared. Results The total effective rate of the study group was 97.00% higher than that of the control group(55.00%), and the difference was statistically significant(P<0.05). Operation time, intraoperative blood loss, postoperative exhaust time, time to get out of bed, length of hospital stay and pain score were(67.95±5.30) min,(57.24±3.28) ml,(11.53±2.64) h,(21.10±3.25) h,(5.23±1.35) d and(3.10±1.24) score, the control group respectively was(114.23±6.23) min,(98.30±6.24) ml,(32.48±4.90) h,(53.12±5.13) h,(10.43±4.63) d,(9.24±2.64) score. The operation time, postoperative exhaust time, getting out of bed time and hospitalization time of the study group were shorter than those of the control group, the intraoperative blood loss was less than that of the control group, and the pain score was lower than that of the control group, the difference was statistically significant(P<0.05). The complication rate of the study group was lower than that of the control group, and the difference was statistically significant(P<0.05). The indexes of norepinephrine(NE), angiotensin II(Ang-Ⅱ) and endothelin-1(ET-1) in study group were lower than those in control group, and the difference was statistically significant(P<0.05). Conclusion Laparoscopic removal of uterine fibroids is more effective than traditional surgery, with significant clinical efficacy, faster postoperative recovery and lower incidence of complications.