中西医结合治疗对盆腔炎致慢性疼痛患者疗效及对炎症因子影响的研究

Study on the Effect of Integrated Chinese and Western Medicine on Chronic Pain Caused by Pelvic Inflammatory Disease and Its Influence on Inflammatory Factors

目的 分析盆腔炎致慢性疼痛患者采用中西医结合治疗对其效果和炎症因子水平的影响。方法 选取120例盆腔炎致慢性疼痛患者为研究对象,根据随机数字表法将患者分为试验组与对照组,每组60例。对照组采用常规西医抗感染治疗,试验组采用中西医结合治疗。比较两组治疗前后炎症因子水平(C反应蛋白、白介素-6、白介素-8、白介素-1β及肿瘤坏死因子-α)、疼痛程度和临床疗效。结果 试验组临床治疗总有效率(91.67%)高于对照组(71.67%),差异有统计学意义(P<0.05)。治疗后,两组C反应蛋白、白介素-6、白介素-8、白介素-1β及肿瘤坏死因子-α水平均明显低于治疗后,且试验组C反应蛋白、白介素-6、白介素-8、白介素-1β及肿瘤坏死因子-α水平均低于对照组,差异有统计学意义(P<0.05)。试验组疼痛数字评分为(3.7±1.3)分,对照组为(7.9±2.9)分,试验组疼痛数字评分低于对照组,差异有统计学意义(P<0.05)。结论 采用中西医结合治疗盆腔炎致慢性疼痛患者可缓解患者的临床症状,改善炎症因子水平,提高临床疗效,具有较高的推广和应用价值。

Objective To analyze the effect of integrated Chinese and western medicine on chronic pain caused by pelvic inflammatory disease and the level of inflammatory factors. Methods 120 patients with chronic pain caused by pelvic inflammatory disease were selected as the research objects. According to the random number table method, the patients were divided into experimental group and control group, with 60 cases in each group. The control group was treated with conventional anti-infective Western medicine, and the experimental group was treated with integrated Chinese and western medicine. The levels of inflammatory factors(C-reactive protein, interleukin-6, interleukin-8, interleukin-1β and tumor necrosis factor-α), pain degree and clinical efficacy were compared between the two groups before and after treatment. Results The total effective rate of the experimental group(91.67%) was higher than that of the control group(71.67%), the difference was statistically significant(P<0.05). After treatment,C-reactive protein, interleukin-6, interleukin-8, interleukin-1β and tumor necrosis factor-α in 2 groups were significantly lower than after treatment, and C-reactive protein, interleukin-6, interleukin-8, interleukin-1β and tumor necrosis factor-α in the experimental group were lower than those in the control group, the difference was statistically significant(P<0.05). The pain number score was(3.7±1.3) points in the experimental group and(7.9±2.9) points in the control group. The pain score of the experimental group was lower than that of the control group, and the difference was statistically significant(P<0.05). Conclusion The use of integrated Chinese and western medicine in the treatment of chronic pain caused by pelvic inflammatory disease can not only relieve the clinical symptoms of patients, improve the level of inflammatory factors, improve clinical efficacy, has a high value of promotion and application in clinical.