基于银纳米颗粒/铜纳米线复合材料的电化学无酶葡萄糖传感器

Electrochemical non-enzyme glucose sensing based on silver nanoparticles/copper nanowire composites

以抗坏血酸为还原剂在均匀的铜纳米线(CuNWs)表面将硝酸银还原,成功制备出不同负载量的Ag纳米颗粒均匀生长在铜纳米线(AgNPs/CuNWs)上的复合材料.利用循环伏安法检测AgNPs/CuNWs修饰电极对葡萄糖的电催化性能,发现Ag颗粒负载量质量分数为5.57%时具有最佳的电流响应,同时对葡萄糖分子表现出良好的电催化活性,灵敏度高达693.1μA(mmol/L)^(-1) cm^(-2),宽线性范围0.01~4.18 mmol/L,低检测限为3.4μmol/L(S/N>3),对血液中的一些干扰物具有出色的抗干扰性,并具有超过两周的高稳定性.此无酶葡萄糖传感器表现出良好的稳定性和高选择性,在电化学无酶葡萄糖检测中具有良好的应用前景.

Using ascorbic acid as the reducing agent,to reduce AgNO_(3) on the surface of the uniform copper nanowires(CuNWs),different loadings of Ag nanoparticles on the copper nanowires(AgNPs/CuNWs)were successfully synthesized.By cyclic voltammetry,it was found that the electrode modified by AgNPs/CuNWs with Ag loading of 5.57%had the best current response and exhibited good electrocatalytic activity for glucose,with a sensitivity as high as 693.1μA(mmol/L)^(-1) cm^(-2),wide linear range from 0.01 to 4.18 mmol/L,low detection limit of 3.4μmol/L(S/N>3),excellent immunity to some important interfering substances in blood,and had more than two weeks of high stability.The non-enzyme glucose sensor exhibits good stability and high selectivity,and it has good application prospects in electrochemical non-enzyme glucose detection.