摘要
通过查阅近几年国内外文献,对诃子的化学成分、药理作用及机制、质量控制和炮制研究进展进行综述。诃子内所含化学成分丰富多样,其中含鞣质、酚酸、三萜类成分居多。现代中药药理学研究表明具有抗菌、抗氧化、抗肿瘤等多种药理作用。本文系统阐述了诃子的化学成分、药理作用及机制、质量标准、炮制研究以及其自身安全性,为临床科学合理用药和进一步对诃子的深入开发应用提供理论依据。
Based on domestic and foreign literatures in recent years,this paper systematically gave a review on the advance of studies for chemical composition,pharmacological action and mechanism,quality control and processing of T.chebula.The main chemical components of T.chebula include tannins,phenolic acids and triterpenoids.Modern pharmacological studies have shown that T.chebula extract has many pharmacological activities,such as anti-microbial,detoxification,anti-cancer,anti-oxidation,protecting the brain,liver and gastrointestinal mucosa,detoxify aconite.In this paper,the chemical composition,pharmacological action and mechanism,quality standard,processing research and its own safety of T.chebula are systematically described,providing theoretical basis for scientific and rational use of T.chebula and further development and application of T.chebula.
作者
李华爽
刘永建
杨洪柳
刘永刚
LI Hua-shuang;LIU Yong-jian;YANG Hong-liu;LIU Yong-gang(Beijing University of Traditional Chinese Medicine,Beijing 100000,China)
出处
《天然产物研究与开发》
CAS
CSCD
2022年第12期2130-2141,共12页
Natural Product Research and Development
基金
国家自然科学基金(82130113)。
关键词
诃子
有效化学成分
药理作用
作用机制
安全性
质量评价
Terminalia chebula
effective chemical composition
pharmacological action
mechanism of action
security
quality evaluation