基于四项行动法延伸护理对多囊卵巢综合征患者体外受精妊娠结局的影响

Effect of Extended Nursing Based on Four Action Methods on in Vitro Fertilization Pregnancy Outcome of Patients with Polycystic Ovary Syndrome

目的 探讨基于四项行动法延伸护理对多囊卵巢综合征(PCOS)患者体外受精妊娠结局的影响。方法 选取2020年1月至2021年1月在我院接受体外受精的100例PCOS患者为研究对象,按照随机分组的方式分为观察组和对照组,每组各50例。对照组患者采用常规干预,观察组患者采用四项行动法延伸护理干预。比较两组妊娠结局、控制性超排卵情况、焦虑状态。结果 两组妊娠结局显示,观察组在受精率、优胚率方面略高于对照组,但数据差异不具统计学意义(P均> 0.05),而观察组种植率和妊娠率显著高于对照组,数据差异具有统计学意义(P均<0.05);两组控制性超排卵显示,观察组在促性腺激素时间、HCG子宫内膜厚度、促性腺激素用量和获卵数方面均优于对照组,但数据差异不具统计学意义(P均> 0.05);干预前,两组状态焦虑评分、特质焦虑评分相比无显著差异(P均>0.05),干预后,两组状态焦虑评分、特质焦虑评分均明显降低,且观察组降低水平明显优于对照组(P均<0.05)。结论 对PCOS患者体外受精期间应用四项行动法延伸护理有利于改善妊娠结局,尤其是在种植率、妊娠率方面更具优势。

Objective To explore the effect of extended nursing based on four action methods on in vitro fertilization pregnancy outcome of patients with polycystic ovary syndrome(PCOS). Methods 100 patients with PCOS who received in vitro fertilization in our hospital from January 2020 to January 2021 were selected as the research object, and randomly divided into observation group and control group, 50 cases in each group. Patients in control group were treated with routine intervention, and patients in observation group were treated with extended nursing intervention of four action methods. Pregnancy outcome, controlled superovulation and anxiety were compared between the two groups. Results The comparison of pregnancy outcomes between the two groups showed that the fertilization rate and optimal embryo rate in the observation group were slightly higher than those in the control group, but the differences were not statistically significant(P>0.05), while the planting rate and pregnancy rate in the observation group were significantly higher than those in the control group, the differences were statistically significant(P<0.05). Comparison of controlled superovulation between the two groups showed that the observation group was better than the control group in gonadotropin time, HCG endometrial thickness, gonadotropin dosage and egg quantity, but the differences were not statistically significant(all P>0.05). Before intervention,there were no significant differences in state anxiety score and trait anxiety score between the two groups(P>0.05), but after intervention, the state anxiety score and trait anxiety score of the two groups were significantly reduced, and the reduction level of the observation group was significantly better than the control group(P<0.05). Conclusion Extended nursing of PCOS patients during in vitro fertilization with four action methods is beneficial to improve pregnancy outcome, especially in terms of implantation rate and pregnancy rate.