显微镜下手术切除脑胶质瘤后患者的康复情况分析

Rehabilitation analysis of patients with gliomatosis cerebri after surgical resection under microscope

目的:探讨显微镜下手术切除脑胶质瘤(GC)后对患者脑脊液神经肽类物质及康复的影响。方法:选择88例GC患者,按随机数字表法将其分为两组,每组44例。对照组采用开颅手术切除肿瘤治疗,观察组采用显微镜下手术切除肿瘤治疗。比较两组脑脊液神经肽类物质水平、下床及住院时间、并发症。结果:术后,观察组β-内啡肽(β-EP)、催产素(OT)、精氨酸加压素(AVP)水平均高于对照组,差异有统计学意义(P<0.05);观察组下床时间、住院时间均短于对照组(P<0.05);观察组并发症发生率4.5%低于对照组18.2%,差异有统计学意义(P<0.05)。结论:GC患者采用显微镜下手术切除治疗,损伤小、并发症低,术后康复快。

Objective: To investigate the effects of microscopic surgical resection of gliomatosis cerebri(GC) on the level of neuropeptides in cerebrospinal fluid and the rehabilitation in patients. Methods: A total of 88 GC patients were selected and randomized into two groups, each with 44 cases. The control group received craniotomy, while the observation group underwent microscopic surgical resection. Then, levels of neuropeptides of cerebrospinal fluid, time of getting out of bed, hospital stay, and complications were compared between patients in both groups. Results: After operation, the β-endorphin(β-EP), oxytocin(OT) and the arginine vasopressin(AVP) levels in the observation group were higher than those of the control group, and the differences were statistically significant(P<0.05);and the time for patients to get out of bed and the length of hospital stay was shorter than that in the control group(P<0.05);and the total complication rate of the observation group was 4.5%, which was lower than 18.2% in the control group, and the difference was significant( P<0.05). Conclusion: Microscopic surgical resection for GC patients has less damage and fewer complications, and quick recover after surgery.