中药坐浴在原发性肛门瘙痒症中的应用价值

Application value of traditional Chinese medicine sitz bath in patients with primary anal pruritus

目的:探讨原发性肛门瘙痒症患者应用中药坐浴的效果。方法:以109例原发性肛门瘙痒症患者作为研究对象,随机分为对照组和观察组。对照组54例给予高锰酸钾坐浴,观察组55例在对照组基础上增加中药坐浴。比较并分析两组患者的症状评分、血清β-内啡肽、亮氨酸脑啡肽和复发情况。结果:观察组患者皮肤苔藓样病变、肛门瘙痒、皮肤湿疹样病变评分均低于对照组,差异有统计学意义(P<0.05);观察组患者β-内啡肽、亮氨酸脑啡肽水平均高于对照组(P<0.05);干预后6个月观察组复发率低于对照组(P<0.05)。结论:中药坐浴可有效减轻原发性肛门瘙痒症患者临床症状,降低复发率。

Objective: To investigate the effect of sitz both with traditional Chinese medicine on patients with primary anal pruritus. Methods: 109 patients with primary anal pruritus were randomly divided into the control group and observation group. 54 cases in the control group were given sitz bath with potassium permanganate, while another 55 cases in the observation group were given sitz bath with Chinese medicine on the basis of the control group. The symptom scores, serum β-endorphin, leucine enkephalin levels and recurrence of patients were compared between the two groups. Results: The scores of skin lichenoid lesions, pruritus ani and skin eczematoid lesions in the observation group were lower than those in the control group, and the differences were statistically significant(P<0.05);the levels of β-endorphin and leucine enkephalin in the observation group were higher than those in the control group(P<0.05);and the recurrence rate of the observation group 6 months after intervention was lower than that of the control group(P<0.05).Conclusion: Sitz both with traditional Chinese medicine can effectively relieve the clinical symptoms and reduce the recurrence rate of patients with primary anal pruritus.