分级护理在急性酒精中毒患者护理中的应用效果

Effect of graded care in patients with acute alcoholic intoxication

目的探讨分级护理在急性酒精中毒患者护理中的应用效果,以期为临床治疗提供参考。方法本研究选取福建医科大学附属南平第一医院2020年9月—2022年2月接诊的102例急性酒精中毒患者为研究对象。2020年9月—2021年4月收治的患者归为对照组,2021年5月—2022年2月收治的患者归为观察组。对照组患者采用常规护理。观察组患者采用分级护理。比较2组患者护理前及出院时肝功能相关指标[谷丙转氨酶(ALT)、谷草转氨酶(AST)]、肾功能相关指标[血清尿素(SUN)、血肌酐(SCr)]水平。比较2组患者护理前及出院时心肌损伤标志物[一氧化氮合酶(i NOS)、超氧化物歧化酶(SOD)、还原型谷胱甘肽(GSH)]水平。比较2组患者苏醒后的不良事件发生情况。结果护理前,2组患者ALT、AST、BUN、SCr水平比较,差异无统计学意义(P>0.05)。出院时,2组患者ALT、AST、BUN、SCr水平均低于护理前,且观察组低于对照组,差异均有统计学意义(P<0.05)。护理前,2组患者i NOS、SOD、GSH水平比较,差异无统计学意义(P>0.05)。出院时,2组患者SOD、GSH水平均高于护理前,且观察组高于对照组,差异均有统计学意义(P<0.05)。出院时,2组患者i NOS水平均低于护理前,且观察组低于对照组,差异均有统计学意义(P<0.05)。观察组患者不良事件发生率为7.84%,低于对照组的23.52%,差异有统计学意义(P<0.05)。结论分级护理干预可增强急性酒精中毒患者的治疗效果,对改善患者预后也有积极意义,值得临床推广应用。

Objective The objective of this paper is to explore the effect of graded care in the nursing of patients with acute alcoholic intoxication,so as to provide evidence for clinical treatment.Methods A total of 102 patients with acute alcoholic intoxication admitted to the Nanping First Hospital Affiliated to Fujian Medical University from September 2020 to February 2022 were selected as the study participants.Patients admitted from September 2020 to April 2021 were selected in the control group,and patients admitted from May 2021 to February 2022 were selected in the observation group.Patients in the control group received routine care and patients in the observation group graded care.The levels of liver function-related indexes[alanine aminotransferase(ALT),aspartate aminotransferase(AST)]and renal function-related indexes[serum urea(SUN),serum creatinine(SCr)]before care and at discharge were compared between the two groups.The levels of inducible nitric oxide synthase(i NOS),superoxide dismutase(SOD),and reduced glutathione(GSH)were compared between the two groups before care and at discharge.The incidence of adverse events after awakening was compared between the 2 groups.Results Before care,there was no significant difference in ALT,AST,BUN,and SCr levels between the two groups(P>0.05).At discharge,the levels of these indexes in the 2 groups were significantly lower than those before care,with the observation group significantly lower than the control group(P<0.05).Before care,there was no significant difference in i NOS,SOD,and GSH levels between the 2 groups(P>0.05).At discharge,the levels of SOD and GSH in the 2 groups were significantly higher than those before care,with the observation group significantly higher than the control group(P<0.05).At discharge,i NOS levels were significantly lower in both groups than those before care and were significantly lower in the observation group than in the control group(P<0.05).The incidence rate of adverse events in the observation group was 7.84%,which was significantly lower than that in the control group(23.52%,P<0.05).Conclusion Graded care intervention can enhance the therapeutic effect of patients with acute alcoholic intoxication and has positive impacts on improving the prognosis of patients.These benefits hold promise for a wider application of this procedure clinically.