犬小孢子菌致儿童白癣及母亲体癣1例

Tinea capitis in a child and tinea corporis in the mother caused by Microsporum canis

患儿,女,2岁,头皮红斑、丘疹、鳞屑伴脱发4个月。患儿母亲29岁,背部鳞屑性红斑伴痒2周。患儿断发与母亲背部鳞屑真菌镜检及培养均阳性。分子生物学菌种鉴定,两株均为犬小孢子菌,同源性100%。诊断:犬小孢子菌所致白癣(患儿);体癣(母亲)。患儿治疗选择伊曲康唑胶囊口服0.06 g/d、卢立康唑与复方酮康唑乳膏外用及酮康唑洗剂等,总疗程2个月,患儿皮损消退,断发重新长出,真菌镜检与培养阴性。患儿母亲治疗选择卢立康唑与复方酮康唑乳膏外用,3周后背部皮损消退,真菌镜检阴性。停药后随访1年患儿与母亲皮损均无复发。

A 2-year-old girl presented with scalp erythema,papules,scales and alopecia for 4 months.The child’s mother was 29 years old and had scaly erythema with itching on the back for 2 weeks.Microscopic examination and culture of broken hair of the child and the mother’s back sample were positive.Molecular biological identification showed that both strains were Microsporum canis with 100% homology.Oral itraconazole capsule 0.06 g/d,external application of luiconazole and compound ketoconazole cream,and ketoconazole lotion were selected for the treatment of the child.After a total course of 2 months,the child’s skin lesions subsided,and the broken hair regrew.Microscopy and culture were negative.The mother was treated with external use of luiconazole and compound ketoconazole cream.The skin lesions on the back subsided after 3 weeks,and the microscopic examination of fungi was negative.There was no recurrence of skin lesions in the child and her mother during a year follow-up.