中医药治疗失眠伴认知功能障碍的研究进展

Research Progress on Treating Insomnia with Cognitive Dysfunction in TCM

失眠伴认知功能障碍是指在失眠的基础上病情进一步发展,出现记忆力下降、注意力不集中、智力减退、反应迟钝甚至呆傻愚笨等认知功能损伤的表现。失眠伴认知功能障碍较单纯失眠而言危害更大、预后更差,给家庭和社会带来沉重负担。目前西医对失眠伴认知功能障碍的具体作用机制认识不明,缺乏特异性治疗,暂以治疗失眠延缓或阻止认知功能损伤的发生为治疗原则,疗效不突出。近年来,中医药防治失眠伴认知功能障碍的研究日益增多且疗效可观,为本病的临床诊疗提供新的思路。文章整理经典古籍和相关文献中对于失眠伴认知功能障碍的论述,初步探讨了该病的病因病机,着重介绍了中药汤剂和中医适宜技术的研究进展,以期为临床应用与研究提供借鉴。

Insomnia with cognitive dysfunction is defined as the condition progressing further on the basis of insomnia, with manifestations of cognitive impairment, including memory decline, poor concentration, mental retardation, unresponsiveness, and even stupidity.Compared with insomnia, insomnia with cognitive impairment is more harmful and has a worse prognosis, resulting in a heavy burden on families and society.At present, the specific mechanism of insomnia with cognitive dysfunction is unknown, and Western medicine lacks specific treatment for it, temporarily take treating insomnia, delaying or preventing cognitive impairment as the treatment principle, and its efficacy is not prominent.In recent years, there has been an increasing number of studies on the prevention and treatment of insomnia with cognitive dysfunction in traditional Chinese medicine(TCM), and the efficacy is considerable, which provides a new idea for the clinical diagnosis and treatment of this disease.This article collates statements of insomnia with cognitive dysfunction from classic ancient books and related literatures, preliminarily explores the etiopathogenesis of this disease, and highlights the research progress of TCM Decoction and appropriate technology, with a view to provide evidences for clinical application and research.