处方点评对抗菌药物合理应用的影响分析

Analysis of the effect of prescription review on rational use of antimicrobial agents

目的 探讨处方点评对抗菌药物合理应用的影响。方法 抽取2016年1~12月150张未实施处方点评的抗菌药物处方作为对照组;另抽取2017年1~12月150张实施处方点评的抗菌药物处方作为研究组。分析两组抗菌药物使用情况以及不合理使用情况。结果 研究组注射用抗菌药物使用率9.33%、抗菌药物联合使用率3.33%,均低于对照组的24.67%、14.67%,处方合格率98.00%高于对照组的84.67%,差异有统计学意义(P<0.05)。研究组无指征用药占比0.67%,用法、用量不适宜占比0.67%,溶媒不适宜占比0,联合用药不适宜占比0.67%,配伍禁忌占比0,均低于对照组的4.67%、5.33%、4.67%、4.67%、2.67%,差异有统计学意义(P<0.05)。结论 处方点评对于提高抗菌药物的合理应用水平具有非常重要的作用。

Objective To discuss the influence of prescription review on the rational use of antimicrobial agents.Methods 150 prescriptions of antimicrobial agents that did not implement prescription review from January to December 2016 were taken as the control group;another 150 prescriptions of antimicrobial agents that implemented prescription review from January to December 2017 were taken as the research group.The use of antimicrobial drugs and irrational use of antimicrobial drugs were compared between the two groups.Results In the research group,the usage rate of antimicrobial agents for injection was 9.33% and the combined usage rate of antimicrobial agents was 3.33%,which were lower than 24.67% and 14.67% in the control group;the prescription qualification rate was 98.00%,which was higher than 84.67% in the control group;and the differences were statistically significant(P<0.05).In the research group,0.67% of medications were used without indications,0.67% of inappropriate usage and dosage,0.67% of inappropriate solvents,0.67% of inappropriate combination medications,and 0 of contraindications,all of which were lower than 4.67%,5.33%,4.67%,4.67%,and 2.67% in the control group,and the differences were statistically significant(P<0.05).Conclusion Prescription review is is great importance to improve the rational use of antimicrobial agents.