不同类型肺肿瘤气道播散的研究现况

Research Status of Spread Through Air Spaces in Different Types of Lung Tumors

世界卫生组织在2015年提出气道播散(spread through air spaces,STAS)这一概念作为肺腺癌一种新的侵袭模式,在后续研究中发现STAS也存在于其他类型肺肿瘤中。随着对肺肿瘤研究的不断深入,STAS被认为是影响其预后的重要因素。本文对STAS在不同类型肺肿瘤中的定义、分类、发生机制、病理亚型、影像学表现、基因表达和生存预后等方面的研究进行综述。

The World Health Organization proposed the concept of spread through air spaces(STAS) as a new invasive mode of lung adenocarcinoma in 2015. In subsequent studies, it was found that STAS also exists in other types of lung tumors. With the development of research on lung tumor, STAS is considered to be an important factor affecting the prognosis. This paper reviews the studies on the definition, classification, pathogenesis,pathological subtypes, imaging manifestations, gene expression, survival and prognosis of STAS in different types of lung tumors.