2013-2017年陕西省肿瘤登记地区肺癌发病与死亡趋势分析

Trends of Incidence and Mortality of Lung Cancer in Shaanxi Cancer Registration Areas from 2013 to 2017

[目的]分析陕西省2013-2017年肿瘤登记地区肺癌的发病、死亡情况以及变化趋势。[方法]收集陕西省26个肿瘤登记地区2013-2017年的肺癌发病、死亡信息,并用Excel2007和Joinpoint Regression Program 4.8.01分析计算城乡、性别、年龄别肺癌发病(死亡)率、标化发病(死亡)率(中标率与世标率)、0~74岁累积发病(死亡)率、35~64岁截缩率以及年度变化百分比(APC)。[结果] 2013-2017年陕西省肿瘤登记地区肺癌发病率为48.16/10万,中标率为31.65/10万,0~74岁累积率为3.82%,35~64岁截缩率为44.53/10万。男性肺癌发病率大于女性,城市肿瘤登记地区肺癌发病率高于农村肿瘤登记地区。肺癌年龄别发病率在40岁以下处于低发阶段,40岁之后快速上升。2013-2017年肺癌死亡率为38.09/10万,中标率为24.94/10万,0~74岁累积率为2.97%,35~64岁截缩率为33.79/10万。男性肺癌死亡率大于女性,城市地区肺癌死亡率高于农村地区。肺癌年龄别死亡率在45岁以前处于较低水平,45岁之后逐渐上升。2013-2017年农村地区肺癌中标死亡率从2013-2017年呈显著上升趋势(APC=5.4%,95%CI:0.4%~10.5%,P<0.05)。[结论]应将陕西省40岁以上城市地区男性作为重点人群进行肺癌防治知识的科普与宣传,加强农村地区肺癌早诊早治工作,遏制农村地区肺癌死亡率上升的发展趋势。

[Purpose] To analyze the trends of lung cancer incidence and mortality rates in Shaanxi cancer registries from 2013 to 2017. [Methods] The incidence and death data of lung cancer in26 tumor registration regions of Shaanxi Province from 2013 to 2017 were collected. The crude incidence(mortality) rate, standardized incidence(mortality) rate by Chinese standard population and Segi’s population(ASRC, ASRW) in 2000, 0~74 years old cumulative incidence(mortality)rate, 35~64 years truncated rate and annual percentage change(APC) of lung cancer were calculated by Excel 2007 and Joinpoint Regression Program 4.8.01. [Results] From 2013 to 2017, the crude incidence rate of lung cancer in cancer registration areas in Shaanxi Province was 48.16/105,the ASRC was 31.65/105, the cumulative rate was 3.82%, and the truncated rate was 44.53/105.The incidence of lung cancer was higher in male than that in female, and higher in urban areas than that in rural areas. The age-specific incidence of lung cancer was in a low stage below 40years old, and increased rapidly after 40 years old. From 2013 to 2017, the crude mortality rate of lung cancer in the cancer registration areas of Shaanxi Province was 38.09/105, the ASRC was24.94/105, the cumulative rate was 2.97%, and the truncated rate was 33.79/105. The lung cancer mortality was higher in male than that in female and higher in urban areas than that in rural areas.The age-specific mortality rate of lung cancer was relatively low under 45 years old, and gradually increased after 45 years old. The ASRC of lung cancer mortality in rural cancer registration areas showed an increasing trend from 2013 to 2017(APC=5.4%, 95%CI:0.4%~10.5%,P<0.05). [Conclusion] Urban males over 40 years old in Shaanxi Province should be regarded as the key group for lung cancer prevention and control, meanwhile prevention programs in rural areas should be strengthened to curb the rising trend of lung cancer mortality.