青少年睡眠时型与抑郁症状相关性的系统评价

Association between adolescent chronotype and depressive symptoms:a meta-analysis

目的系统评价青少年睡眠时型与抑郁症状的相关性。方法计算机检索CNKI、VIP、WanFang Data、PubMed、ScienceDirect和Web of Science数据库,搜集有关青少年睡眠时型与抑郁症状关联的研究,检索时限均为建库至2022年1月17日。由2名研究者独立筛选文献、提取资料并评价纳入研究的偏倚风险后,采用Stata 16.0软件进行Meta分析。结果共纳入12个研究。Meta分析结果显示:青少年睡眠时型与抑郁症状之间存在相关性[Fisher’s Z=-0.19,95%CI(-0.21,-0.17),P<0.001]。结论当前证据表明,青少年的夜晚型睡眠时型可能是抑郁发生的危险因素之一。受纳入研究数量和质量的限制,上述结论尚待更多高质量研究予以验证。

Objective To systematically review the association between chronotype and depressive symptoms among adolescents.Methods CNKI,VIP,WanFang Data,PubMed,ScienceDirect and Web of Science databases were electronically searched to collect studies on the association between adolescent chronotype and depressive symptoms from inception to January 17,2022.Two reviewers independently screened literature,extracted data,and assessed the risk of bias of the included studies.Meta-analysis was then performed using Stata 16.0 software.Results A total of 12 studies were included.The results of meta-analysis showed that there was an association between chronotype and depressive symptoms(Fisher’s Z=-0.19,95%CI-0.21 to-0.17,P<0.001).Conclusion Current evidence shows that evening-type chronotype may be a risk factor for depressive symptoms among adolescents.Due to the limited quality and quantity of the included studies,more high-quality studies are needed to verify the above conclusion.