纳布啡联合丙泊酚麻醉对宫腔镜患者术后恢复质量的影响

目的探讨丙泊酚联合纳布啡使用相较于芬太尼对接受宫腔镜手术患者术后恢复质量的影响。方法选取2021年6月至2021年12月在本院行宫腔镜息肉切除术患者60例进行单中心随机双盲对照试验,依照随机数字表法将患者分为两组,每组各30例,分别为丙泊酚+芬太尼(F组),丙泊酚+纳布啡(N组)。采集患者的人口统计学资料,术中血流动力学指标,除干预因素外均质化麻醉管理,术后使用QoR-15量表评估患者的恢复质量,使用视觉模拟量表(VAS)评估患者手术后的急性疼痛程度。结果与F组相比,N组患者术后第一天、第三天的QoR-15评分均较高,差异具有统计学意义(P<0.05);在T2(放置扩阴器时)时间点,与F组相比,N组的心率较高(P<0.05);与F组相比,N组患者术后恶心呕吐的发生率降低(P<0.05)。结论丙泊酚联合纳布啡使用可以提高宫腔镜患者术后恢复质量,能够降低术后恶心呕吐的发生率。

Objective To investigate the effect of propofol combined with naborphine on the quality of postoperative recovery of hysteroscopic patients compared with fentanyl.Methods 60 patients who underwent hysteroscopic polypectomy in our hospital from June 2021 to December 2021 were selected for a single-center randomized double-blind controlled trial.According to the random number table method,the patients were divided into two groups:Propofol+fentanyl(Group F)and propofol+naborphine(Group N),with 30 cases in each group.The preoperative general data and intraoperative hemodynamic data were collected.In addition to intervention factors,homogeneous anesthesia management was used.QoR-15 scale was used to assess the quality of postoperative recovery,and visual analogue scale(visual analogue scale,VAS)was used to assess the degree of postoperative acute pain.Results The QoR-15 scores on the first and third day after surgery in group N was significantly higher than that in group F,with statistical significance(P<0.05),and the heart rate(HR)in group N was higher than that in group N at T2(when placing vaginal dilator)(P<0.05).The incidence of postoperative nausea and vomiting in group N was lower than that in group F(P<0.05).Conclusion Under the condition of this clinical trial,propofol combined with naborphine can improve the recovery quality of patients undergoing hysteroscopic surgery and reduce the incidence of postoperative nausea and vomiting.