急性心肌梗死继发心脏破裂的危险因素分析

Analysis of Risk Factors for Heart Rupture Secondary to Acute Myocardial Infarction

目的关于急性心肌梗死继发心脏破裂的危险因素分析。方法回顾性分析2017年1月至2020年5月到我院进行治疗的1549例急性心肌梗死患者作为调查对象,抽取其中的150例作为本文的调查对象,分析继发心脏破裂的发生率,对所有患者的资料进行总结,调查患者继发心脏破裂的危险因素。结果(1)150例急性心肌梗死患者,继发心脏破裂患者25例,占16.67%。(2)经过单因素分析能够得出,患者的年龄、入院时心率、性别、肌钙蛋白水平、N末端B型钠尿肽前体、尿素、急诊冠状动脉介入(PCI)手术、血红蛋白水平、红细胞计数、应用β受体阻滞剂、血管紧张素转换酶抑制剂(ACEI)/血管紧张素受体阻滞剂(ARB)等为急性心肌梗死继发心脏破裂的单因素,有统计学差异(P<0.05)。(3)经过Logistic多因素回归分析可得:年龄、入院时心率、肌钙蛋白水平、N末端B型钠尿肽前体、尿素、是否进行急诊PCI手术、是否应用β受体阻滞剂、是否应用ACEI/ARB为急性心肌梗死继发心脏破裂的独立危险因素,与其他因素相比,差异明显(P<0.05)。结论临床上导致急性心肌梗死继发心脏破裂的危险因素表现在多个方面,主要为年龄、入院时心率、肌钙蛋白水平、N末端B型钠尿肽前体、尿素、是否进行急诊PCI手术、是否应用β受体阻滞剂、是否应用ACEI/ARB等。所以应该根据患者的实际情况合理采取方法对患者进行干预,这有助于促进患者的病情转归,也能为患者的临床治疗工作提供科学性的参考依据。

Objective To analyze the risk factors of cardiac rupture secondary to acute myocardial infarction.Methods A retrospective analysis of 1549 patients with acute myocardial infarction who came to our hospital for treatment from January 2017 to May 2020 was selected as the object of investigation,and 150 of them were selected as the object of this study to analyze the incidence of secondary cardiac rupture.The data of all patients were summarized and the risk factors for secondary cardiac rupture were investigated.Results(1)Among the 150 patients with acute myocardial infarction,25 had secondary cardiac rupture,accounting for 16.67%.(2)Univariate analysis showed that the age,heart rate,gender,troponin level,N-terminal B-type natriuretic peptide precursor,urea,emergency coronary intervention(PCI)surgery,hemoglobin level,red blood cell count,use of beta-blockers,angiotensin-converting enzyme inhibitor(ACEI)/angiotensin receptor blockers(ARB)and other factors are the single factors of cardiac rupture secondary to acute myocardial infarction,with statistical difference(P<0.05).(3)Age,heart rate at admission,troponin level,N-terminal B-type natriuretic peptide precursor,urea,whether emergency PCI surgery is performed,whether beta-blockers are used,and whether ACEI/ARB is used are independent risk factors for cardiac rupture secondary to acute myocardial infarction,compared with other factors,the difference is significant(P<0.05).Conclusion The clinical risk factors of cardiac rupture secondary to acute myocardial infarction are manifested in many aspects,mainly including age,heart rate at admission,troponin level,N-terminal B-type natriuretic peptide precursor,urea,whether emergency PCI is performed or not,whether to use beta-blockers,whether to use ACEI/ARB,etc.Therefore,it is necessary to take reasonable measures to intervene patients according to the actual situation of patients,which will help to promote the prognosis of patients,and can also provide a scientific reference for the clinical treatment of patients.