妊娠期糖尿病与肠道菌群改变的研究进展

Advances in the study on gestational diabetes mellitus and changes in intestinal flora

妊娠期糖尿病(GDM)是妊娠常见并发症之一,表现为妊娠期糖代谢异常,对母儿造成长久的影响。妊娠期孕妇肠道菌群数量和种类出现生理性改变。研究表明,肠道菌群多样性及丰富度的改变是造成GDM发生发展的潜在因素。该文对GDM女性菌群改变的研究文献作一综述。

Gestational diabetes mellitus(GDM)is one of the common complications of pregnancy,which manifests as abnormal glucose metabolism during pregnancy and causes profound effects on pregnant women and their fetuses.Physiological changes in the number and type of intestinal flora occur during pregnancy,and numerous studies have showed that changes in the diversity and abundance of intestinal flora are potential contributing factors to the development of GDM.In this paper,we review the literature on the changes in intestinal flora of women with GDM.