基于土壅木郁探讨肠道微生物稳态失衡与肝癌的关系

Exploration on Relationship between Intestinal Microbial Homeostasis Imbalance and Liver Cancer Based on Earth Stagnation Wood Depression

人体内肠道微生物稳态的变化,与肝癌发生、发展息息相关。“土壅木郁”作为五行学说的重要部分,诠释了肝脾之间在生理和病理上的紧密作用。同时,肝失疏泄会导致或加重肝癌,肠道微生物产生的机制是中医“脾”维持正常生理功能的基础。文章基于“土壅木郁”理论阐述的肝脾关系,探讨肠道微生物稳态失衡对肝癌的影响。拟在为防治肝癌提出新视角和理论支持。

The changes of intestinal microbial homeostasis in human body are closely related to the occurrence and development of liver cancer.As an important part of the theory of five elements,"Earth stagnation,wood depression"interprets the close physiological and pathological role between the liver and spleen.At the same time,liver failing to maintain the normal flow of Qi can cause or aggravate liver cancer,and the mechanism of intestinal microorganism production is the basis for TCM"spleen"to maintain normal physiological function.Therefore,based on the relationship between liver and spleen described by the theory of"Earth stagnation,wood depression",this paper discusses the effect of intestinal microbial homeostasis imbalance on liver cancer.It is intended to provide new perspective and theoretical support for the prevention and treatment of liver cancer.