摘要
MicroRNAs(miRNAs)是一种小的非编码RNA,可以调控基因的表达,从而调节细胞的生物过程。越来越多的证据表明,miRNA在慢性阻塞性肺疾病(chronic obstructive pulmonary disease, COPD)的发生、发展中发挥重要的作用。本文就miRNA对肺的结构细胞与免疫细胞生物过程的调节作用进行阐述,为COPD的诊断、治疗提供新的见解。
MicroRNAs(miRNAs) are small non-coding RNAs that regulate the expression of genes and thus regulate cellular biological processes. More and more evidences show that miRNA plays an important role in the occurrence and development of chronic obstructive pulmonary disease(COPD). In this paper, the regulation of miRNA on lung structural cells and immune cell biological processes is described, providing new insights for the diagnosis and treatment of COPD.
作者
武国英
高笑宇
杨琼
靳超逸
孙德俊
WU Guoying;GAO Xiaoyu;YANG Qiong;JIN Chaoyi;SUN Dejun(Inner Mongolia Medical University,Hohhot 010110 China;Key Laboratory of National Health Commission for the Diagnosis Treatment of COPD,The People's Hospital of Inner Mongolia Autonomous Region,Hohhot O1oo17 China)
出处
《内蒙古医学杂志》
2022年第9期1077-1081,共5页
Inner Mongolia Medical Journal
基金
国家自然科学基金(编号:81960013)
中央引导地方科技发展资金项目(编号:ZYZ20200486)
中国医学科学院中央级公益性科研院所基本科研业务费专项资金资助项目(编号:2019PT350001)。
