植物基因选择性剪接:断舍离合,达权知变

Alternative Splicing of Plant Genes:Full of Change,Sail with Wind

选择性剪接是基因转录后的mRNA通过不同的剪接方式产生多样性成熟转录本的过程,是真核生物细胞中一种重要的转录后调控方式。植物基因也常通过这种断舍离合的方式产生一专多能的转录本,达到调节多种生命活动的目的。相较于动物,植物中该领域的研究起步较晚,但近年来也取得了长足的进步。该文综述了植物基因选择性剪接的生物学意义、剪接方式和机制、研究方法以及在生长发育与环境胁迫适应性调节中的作用,并展望了未来的研究方向。

Alternative splicing is a process in which the mRNA precursor produces a variety of mature transcripts through different splicing mode.It is an important way in post transcriptional regulation in eukaryotic cells.Plant genes also can produce diverse transcripts via alternative splicing on the same gene,so as to regulate a variety of biological processes.In plants,the research on this field lags behind that in animals,but great progresses have been made in recent years.In this review,we summarized the biological significance,splicing patterns,research methods of the alternative splicing,as well as its roles in the regulation in the growth,development and responses to environmental stresses.Some perspectives and prospects are give for this research field.