CASIA 2与IOLMaster 700测量眼前段参数的比较

Comparison of CASIA 2 and IOLMaster 700 for Measuring the Anterior Segment Data

目的:比较新型扫频源眼前节相干光层析成像仪CASIA 2与扫频源光相干生物测量仪IOLMaster 700测量眼前段结构参数的差异性和一致性。方法:回顾性研究。选取2020年4—5月在天津医科大学眼科医院就诊的白内障患者95例(95眼),分别采用CASIA 2和IOLMaster 700测量中央角膜厚度(CCT)、前房深度(ACD)、晶状体厚度(LT)、角膜曲率陡峭轴(Ks)、角膜曲率平坦轴(Kf)。采用配对样本t检验比较2种仪器对CCT、ACD、LT、Ks、Kf测量结果的差异性;采用Pearson检验分析各参数测量结果在2种仪器间的相关性;采用Bland-Altman法评价各参数测量结果在2种仪器之间的一致性。结果:CASIA 2和IOLMaster 700测量CCT、ACD、LT差异均有统计学意义(t=-11.94,P<0.001;t=8.52,P<0.001;t=-2.97,P=0.004);测量Ks、Kf差异无统计学意义;2种仪器间测量的CCT、ACD、LT、Ks、Kf均呈正相关(r=0.99、0.99、0.99、0.98、0.97,均P<0.001)。Bland-Altman一致性分析显示,2种仪器测量CCT、ACD、LT差值的均数分别为-7.516μm、0.043 mm、0.023 mm,95%一致性界限(LoA)分别为(-19.92,4.48)μm、(-0.055,0.139)mm、(-0.120,0.160)mm。2种仪器测量Ks、Kf差值的均数为0.028 D、0.061 D,95%LoA分别为(-0.65,0.77)D、(-0.52,0.58)D;在95%LoA外分别占了7.36%(7/95)、6.31%(6/95),一致性较差。结论:CASIA 2和IOL Master 700的眼前节参数测量结果存在一定差异,且一致性欠佳。

Objective:To evaluate the difference and the consistency of the ocular anterior segment parameters measured with CASIA 2 and IOLMaster 700 in patients with cataract.Methods:In this retrospective study,95 eyes of 95 patients underwent pre-operative examination for cataract surgery from April 2020 to May 2020 were involved.The central corneal thickness(CCT),anterior chamber depth(ACD),lens thickness(LT),keratometry of the steepest meridian(Ks)and keratometry of the flattest meridian(Kf)measured by CASIA 2 and IOLMaster 700 were documented and analyzed using paired t test for differences,Pearson's test for correlation and Bland-Altman test for consistency.Results:The differences of CCT,ACD and LT values measured by CASIA 2 and IOLMaster 700 were statistically significant(t=-11.94,P<0.001;t=8.52,P<0.001,t=-2.97,P=0.004,respectively),while the differences of Ks and Kf were not statistically significant.The CCT,ACD,LT,Ks and Kf values measured with two instruments were significantly correlated(r=0.99,0.99,0.99,0.98 and 0.97,all P<0.001).Bland-Altman analysis showed that the mean differences of CCT,ACD and LT were-7.516µm、0.043 mm、0.023 mm,respectively.The limits of agreement(LoA)were-19.92,4.48µm,-0.055,0.139 mm,-0.120,0.160 mm.The mean differences of Ks and Kf from the two instruments were 0.028 D and 0.061 D,respectively.The 95%LoA were-0.65,0.77 D and-0.52,0.578 D.The proportion outside 95%LoA were 7.36%(7/95)and 6.31%(6/95).The values of CCT,ACD,LT,Ks and Kf measured by the two instruments were not consistent.Conclusion:The CCT,ACD,LT,Ks and Kf measured with CASIA 2 and IOLMaster 700 were not consistent.