双模态超声在乳腺癌前哨淋巴结转移风险评估中的应用价值

Application value of dual mode ultrasound in evaluating the risk of sentinel lymph node metastasis in breast cancer patients

目的探讨双模态超声(常规彩色多普勒超声联合经皮超声造影)在乳腺癌前哨淋巴结转移风险评估中的应用价值。方法分析62例术后病理诊断为浸润性乳腺癌患者的临床资料,评估常规彩色多普勒超声、经皮超声造影和双模态超声对乳腺癌前哨淋巴结转移风险的诊断价值。结果经皮超声造影检出前哨淋巴结(3.4±0.2)枚,多于常规彩色多普勒超声的(1.7±0.1)枚(P<0.01)。常规彩色多普勒超声诊断前哨淋巴结转移风险的灵敏度为33.33%(3/9),特异度为96.23%(51/53)。经皮超声造影诊断前哨淋巴结转移风险的灵敏度为55.56%(5/9),特异度为92.45%(49/53)。双模态超声诊断前哨淋巴结转移风险的灵敏度为77.78%(7/9),特异度为92.45%(49/53)。结论双模态超声诊断乳腺癌前哨淋巴结转移风险有较高的灵敏度,优于单独常规彩色多普勒超声或经皮超声造影,有望成为术前评估前哨淋巴结转移的有效方法。

Objective To investigate the application value of dual mode ultrasound(conventional color Doppler ultrasound combined with percutaneous contrast-enhanced ultrasound)in evaluating the risk of sentinel lymph node metastasis in the patients with breast cancer.Methods The clinical data of 62 patients with pathological diagnosis of invasive breast cancer were analyzed.The application value of conventional color Doppler ultrasound,percutaneous contrast-enhanced ultrasound and dual mode ultrasound in evaluating the risk of sentinel lymph node metastasis was discussed.Results The number of sentinel lymph nodes detected by percutaneous contrast-enhanced ultrasound was(3.4±0.2)pieces,which was significantly more than(1.7±0.1)pieces detected by conventional color Doppler ultrasound(P<0.01).The sensitivity and specificity of conventional color Doppler ultrasound in diagnosing sentinel lymph node metastasis were 33.33%(3/9)and 96.23%(51/53),which of percutaneous contrast-enhanced ultrasound were 55.56%(5/9)and 92.45(49/53).The sensitivity and specificity of dual mode ultrasound in diagnosing sentinel lymph node metastasis were 77.78%(7/9)and 92.45%(49/53).Conclusion Compared to conventional color Doppler ultrasound or percutaneous contrast-enhanced ultrasound,dual mode ultrasound has higher sensitivity in diagnosing sentinel lymph node metastasis in the patients with breast cancer and is hopeful to become an effective method for assessing the sentinel lymph node metastasis preoperatively.