摘要
血栓性血小板减少性紫癜(TTP)是一种少见的血液系统疾病,其典型的临床表现为血小板减少性紫癜、微血管病性溶血性贫血、神经系统症状、发热及肾脏损害。文中报道2例TTP相关性脑梗死伴发脑微出血的患者及他们共有的特殊影像学表现。2例患者磁共振成像表现出不同时期多发脑梗死,双侧半球、前后循环皆受累,而磁敏感加权成像显示分布于梗死区的脑微出血表现,这种特殊的影像学特征可为及早识别、诊断TTP神经系统受累提供重要线索。
Thrombotic thrombocytopenic purpura(TTP)is a rare hematological disease with typical clinical manifestations of thrombocytopenic purpura,microangiopathic hemolytic anemia,neurological symptoms,fever and kidney damage.Two patients with TTP-associated cerebral infarction complicated with microhemorrhage and their shared specific imaging findings manifestations were reported.The magnetic resonance imaging of the 2 patients showed multiple cerebral infarctions at different stages.Susceptibility-weighted imaging showed cerebral microbleeds in the infarcted area.This special imaging feature can provide important clues for early identification and diagnosis of TTP nervous system injury.
作者
高犇
刘静
王彤
高艳玲
孙海荣
张金彪
Gao Ben;Liu Jing;Wang Tong;Gao Yanling;Sun Hairong;Zhang Jinbiao(Department of Neurology,Affiliated Weihai Municipal Hospital of Shandong University,Weihai 264200,China;Department of Ophthalmology,Affiliated Weihai Municipal Hospital of Shandong University,Weihai 264200,China)
出处
《中华神经科杂志》
CAS
CSCD
北大核心
2022年第12期1402-1407,共6页
Chinese Journal of Neurology
关键词
紫癜
血栓性血小板减少性
磁共振成像
脑微出血
Purpura,thrombotic thrombocytopenic
Magnetic resonance imaging
Cerebral microbleeds