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伴淋巴结转移或远处转移的硬化性肺细胞瘤的临床病理及分子遗传学特征 被引量:1

Clinicopathological and genetic analysis of pulmonary sclerosing pneunocytoma with lymph node metastasis or distant metastasis
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摘要 硬化性肺细胞瘤(pulmonary sclerosing pneumocytoma, PSP)是一种生长缓慢的肺部良性肿瘤。近年, 少量文献报道PSP可发生恶变、淋巴结转移或远处转移, 其临床病理特征与经典的PSP有所差异。同时, 高通量基因检测技术的快速发展提高了人们对该肿瘤的认识, 初步发现PSP的发生发展与PI3K/AKT/mTOR信号通路相关。在此, 笔者回顾总结PSP恶变、伴淋巴结转移或肺外转移的临床病理特征及分子遗传学进展, 以期提高病理医师对所谓"恶性PSP"的警惕, 进而为该肿瘤的治疗决策提供更为有效的科学依据。
作者 万影 蒋莉莉 Wan Ying;Jiang Lili(Department of Pathology,West China Hospital of Sichuan University,Chengdu 610041,China)
出处 《中华病理学杂志》 CAS CSCD 北大核心 2022年第12期1284-1287,共4页 Chinese Journal of Pathology
基金 四川大学华西医院学科卓越发展1·3·5工程临床研究孵化项目(2019HXFH002)。
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