Incident respiratory disease among youths using combustible tobacco,electronic nicotine products,or both:a longitudinal analysis

The use of electronic nicotine products is rapidly evolving among the United States(US)youth.Electronic nicotine products produce and deliver thousands of pulmonary toxicants and iritants different from combustible tobacco[1,2].A review of human,animal,and in vitro experimental studics suggested that electronic nicotine product aerosols can negatively afect multiple aspects of lung cellular and organ physiology,and immune function[3,4].