穴位贴敷联合西药治疗感染后闭塞性细支气管炎疗效观察

Efficacy Observation of Acupoint Application Combined with Western Medication for Post-infectious Bronchiolitis Obliterans

目的观察穴位贴敷联合西药治疗儿童感染后闭塞性细支气管炎的临床疗效及其对血清炎症因子、肺功能指标和胸部高分辨率电子计算机断层扫描(HRCT)结果的影响。方法选取儿童感染后闭塞性细支气管炎患者68例,按随机数字表法分为观察组和对照组,每组34例。两组均予雾化吸入布地奈德和口服阿奇霉素治疗,观察组在此基础上另予穴位贴敷治疗。比较两组临床疗效,观察治疗前后症状体征评分、血氧饱和度指标、肺功能指标、血清炎症因子水平和胸部HRCT评分的变化。结果观察组总有效率为91.2%,明显高于对照组的79.4%,差异具有统计学意义(P<0.05)。观察组治疗后症状和体征评分以及血氧饱和度均优于对照组(P<0.05)。观察组治疗后肺功能指标、血清炎症因子水平及胸部HRCT评分均优于对照组(P<0.05)。结论穴位贴敷联合西药治疗儿童感染后闭塞性细支气管炎临床疗效优于单纯西药治疗,可更好地改善症状和体征,提高血氧饱和度,促进肺功能恢复,改善血清炎症因子水平及胸部HRCT结果。

Objective To observe the clinical efficacy of acupoint application combined with Western medication for post-infectious bronchiolitis obliterans(PIBO)in children and its effects on serum inflammatory factors,pulmonary function parameters,and chest high-resolution computed tomography(HRCT)findings.Method Sixty-eight children with PIBO were randomly divided into an observation group and a control group,with 34 cases in each group.Both groups were given Budesonide for inhalation and oral administration of Azithromycin.In addition,the observation group received acupoint application.Clinical efficacy was compared between the two groups.Before and after the treatment,the symptom and sign scores,oxygen saturation,pulmonary function parameters,serum inflammatory factor levels,and chest HRCT score were observed.Result The total effective rate was 91.2% in the observation group,obviously higher than 79.4% in the control group,and the difference was statistically significant(P<0.05).After the treatment,the observation group was superior to the control group in comparing the symptom and sign scores and oxygen saturation(P<0.05).The observation group also showed advantages over the control group in comparing the pulmonary parameters,serum inflammatory factor levels,and chest HRCT score after the treatment(P<0.05).Conclusion Compared with Western medication alone,acupoint application combined with Western medication can produce more significant clinical efficacy in treating children’s PIBO.This combined therapy can better mitigate symptoms and signs,elevate oxygen saturation,encourage the recovery of pulmonary function,and improve serum inflammatory factor levels and chest HRCT findings.