补喂鞣花酸对哺乳期马驹寄生虫感染情况的影响

Effect of Supplementary Ellagic Acid on Parasitic Infection in Lactating Foals

【目的】研究补喂鞣花酸对哺乳期纯血马马驹肠道寄生虫感染情况的影响,揭示鞣花酸在马属动物消化道寄生虫防治方面的作用,为新型驱虫药物的筛选提供参考依据。【方法】选择平均体重(143.33±16.10) kg、出生日期(±5 d)、寄生虫感染率相近的哺乳期纯血马马驹15匹,随机分为对照组、试验Ⅰ和Ⅱ组,每组5匹。在相同的饲养条件下,对照组马驹不做任何处理,试验Ⅰ组马驹每天补喂15 mg/kg BW鞣花酸,试验Ⅱ组补喂30 mg/kg BW鞣花酸,试验期60 d,分别在试验的第0、15、30、45、60天采集马驹粪便样品,检测各组虫卵种类,统计虫卵数量,并评价驱虫效果。【结果】哺乳纯血马驹感染率高的寄生虫有10种,其中感染率最高的寄生虫是马副蛔虫、马圆线虫及细颈三齿线虫。随着鞣花酸补喂时间的延长及剂量的增加,寄生虫的感染率呈降低趋势,细颈三齿线虫卵、马圆线虫卵、马副蛔虫卵和韦氏类圆线虫卵的排出量显著降低(P<0.05)。补喂鞣花酸后第60天试验Ⅰ和Ⅱ组虫卵总数比对照组分别降低66.59%和97.06%;试验Ⅰ组第30和60天虫卵减少率分别为30.10%和42.97%;试验Ⅱ组第30和60天虫卵减少率分别为37.51%和49.86%。【结论】在本试验条件下,给哺乳马驹补喂鞣花酸能够显著降低寄生虫的感染及粪便中细颈三齿线虫卵、马圆线虫卵、马副蛔虫卵和韦氏类圆线虫卵的排出量,且补喂剂量为30 mg/kg BW效果更佳。

【Objective】 The aim of this study was to explore the effect of supplementary feeding ellagic acid on intestinal parasite infection in foals with pure blood during lactation, reveal the role of tannic acid in the prevention and treatment of digestive tract parasites in equines, and provide references for the screening of new anthelmintic drugs.【Method】 15 lactating pure blood foals with average body weight(143.33 ± 16.10) kg, date of birth(±5 d) and similar parasite infection rate were randomly divided into control group and test groups Ⅰ and Ⅱ,with 5 foals in each group.Under the same feeding conditions, foals in the control group did not receive any treatment, foals in group Ⅰ were supplemented with 15 mg/kg BW of ellagic acid daily, and those in group Ⅱ were supplemented with 30 mg/kg BW of ellagic acid for a 60-day feeding experiment, and foal fecal samples were collected at 0,15,30,45 and 60 days of the experiment to detect egg species, count the number of eggs and evaluate the deworming effect.【Result】 There were 10 species of parasites with high infection rates in mammalian thoroughbred foals, among which the most infected parasites were parasites, equine roundworm and slender-necked trilodonde.With the prolongation of ellagic acid feeding time and the increase of dose, the infection rate of parasites showed a decreasing trend, and the excretion of Trichodon tenuis eggs, Strongylus equi eggs, Parascaris equi and Strongylus westermani eggs were decreased significantly(P<0.05).The EPG values of test groups Ⅰ and Ⅱ were 66.59% and 97.06% lower than those of the control group on the 60 th day after feeding with ellagic acid.The egg reduction rates of the 30 th and 60 th days of test group Ⅰ were 30.10% and 42.97%,respectively.The egg reduction rates in test group Ⅱ were 37.51% and 49.86%,respectively.【Conclusion】 Under the experimental conditions, the supplementary feeding of ellagic acid to suckling foals could significantly reduce the parasite infection and the output of Trichodon tenuis,Strongylus equi,Parascaris equi and Strongylus westermani in feces, and the supplementary feeding dose of 30 mg/kg BW was more effective.