运用筛选工具评价老年共病患者药物相关问题的临床研究

Evaluation and Application Research of Criterion for Drug-related Problems Use in Elderly Patients with Multi-morbidity

目的:通过运用筛选工具,识别和减少老年共病患者药物相关问题(DRPs),优化药物治疗方案,改善多重用药,保障药物治疗安全、有效、经济。方法:随机抽取某医院老年病科2020年1月1日至2021年12月31日诊断为2型糖尿病、高血压病、冠心病的患者35例,运用Beers标准、STOPP标准和中国标准进行评价分析,总结检出的DRPs情况。结果:研究对象年龄(74.8±6.1)岁,服药数量(8.2±2.0)种,32人检出DRPs 62项。其中,与药物有关的DRPs 43项,与疾病状态有关的DRPs 12项,与药物相互作用有关的DRPs 7项。结论:老年共病患者药物相关问题较为突出,临床药师介入药物治疗实施药学监护,能及时发现和消除DRPs,优化药物治疗方案,显著改善患者多重用药,保障患者用药安全。

Objective:To optimize the drug treatment scheme,improve polypharmacy in elderly patients with multi-morbidity,pharmaceutical care used to identify and reduce drug-related problems(DRPs),and ensure the safety,effectiveness and economy of drug treatment.Methods:35 elderly patients with type 2 diabetes,hypertension and coronary heart disease were randomly selected from January 1,2020 to December 31,2021 in the department of general geriatrics.Results:The average age of subjects was(74.8±6.1)years old,and the average number of medication use was(8.2±2.0).A total of 32 patients were detected with 62 DRPs.Among them,43 were DRPs related to medications,12 were DRPs related to disease status and 7 were DRPs related to drug interaction.Conclution:DRPs were serious in elderly patients with multi-morbidity.Clinical pharmacists intervene in medication treatment with pharmaceutical care for elderly patients with multi-morbidity can timely discover and eliminate DRPs,optimize drug regimen,significantly improve polypharmacy,and ensure the safety of patients.