摘要
A recent publication in Cell describes the development and application of engineered virus-like particles(eVLPs)that effh-ciently package and deliver therapeutic gene-editing proteins,including base editors(BEs)and Cas9 nuclease,with the ability to overcome cargo packaging,release,and localization bottlenecks,representing potentially promising.carrier for delivering gene-editing tools of therapeutic interest.
基金
This work was supported by the National Key Research and Development Program of China(2019YFA0111300)
the National Natural Science Foundation of China(51903256,21907113)
the Guangdong Provincial Science and Technology Program(International Scientific Cooperation,2018A050506035)
the Science and Technology Program of Guangz-hou(202102010225)
the Guangdong Province Basic and Applied Basic Research Foundation(2021A1515110534)
the China Postdoctoral Science Foundation(2021M693662)
the Thousand Talents Plan,and the Guangdong Provincial Pearl River Talents Program(2019QN01Y131).
