摘要
Dear Editor,Ferroptosis,an iron-dependent form of programmed cell deathdriven by excessive lipid peroxidation,1has emerged as,apromising andeffective strategy fortrigering cancer celldeath.2,3Insufficient understanding of the role of ferroptosis in melanomaprogression and the tumor microenvironment(TME)has limitedthe development of ferroptosis-targeted therapy and combina-tions with other therapeutic strategies.
基金
This study was supported by the National Key Research and Development Program of China(2019YFE0120800,2019YFA0111600)
the Natural Science Foundation of China for outstanding Young Scholars(82022060)
the National Natural Science Foundation of China(81874242,31800979,82073145)
the Natural Science Foundation of Hunan Province for outstanding Young Scholars(2019J130040)
the National Natural Science Foundation of China(62102455)
China Postdoctoral Science Foundation(2020M682587).