基于孕期血清铁蛋白及血红蛋白水平预防性补铁的效果分析

Effect Analysis of Prophylactic Iron Supplementation Based on Serum Ferritin and Hemoglobin Levels during Pregnancy

目的分析基于孕期血清铁蛋白及血红蛋白水平进行预防性补铁的临床效果。方法选择2019年5月—2021年12月徐州市铜山区中医院接收的60名孕产妇为研究对象,以随机数表法分为两组,30名纳入对照组未施加干预,30名纳入观察组予以预防性补铁治疗。对比两组孕期补铁后SF、Hb水平,铁缺乏引发的不良反应发生率及妊娠结局。结果观察组SF、Hb水平分别为(62.45±12.46)μg/L、(120.61±4.33)g/L,均高于对照组的(41.15±7.39)μg/L、(115.92±4.85)g/L,差异有统计学意义(t=8.053、3.951,P<0.05)。观察组缺铁性贫血及铁缺乏症发生率(10.00%)较对照组(46.67%)低,差异有统计学意义(χ^(2)=9.932,P<0.05)。观察组出血、产后贫血、早产、低体重儿、新生儿窒息等不良妊娠结局发生率为13.33%,低于对照组的50.00%,差异有统计学意义(χ^(2)=9.320,P<0.05)。结论对于孕期女性而言,在其SF<30μg/L但Hb≥110 g/L的情况下予以预防性补铁,可有效预防孕产期及产后贫血的发生,降低不良妊娠结局的发生率。

Objective To analyze the clinical effect of prophylactic iron supplementation based on serum ferritin and hemoglobin levels during pregnancy.Methods 60 pregnant women admitted to Tongshan Hospital of Traditional Chi-nese Medicine in Xuzhou from May 2019 to December 2021 were selected as the research objects and divided into two groups by random number table method.30 were included in the control group without intervention,and 30 were included in the observation group with prophylactic iron supplementation.The levels of SF and Hb,incidence of ad-verse reactions caused by iron deficiency and pregnancy outcomes were compared between the two groups.Results The levels of SF and Hb in the observation group were(62.45±12.46)μg/L and(120.61±4.33)g/L,respectively,which were higher than those in the control group(41.15±7.39)μg/L and(115.92±4.85)g/L,and the differences were statisti-cally significant(t=8.053,3.951,P<0.05).The incidence of iron deficiency anemia and iron deficiency in the observa-tion group(10.00%)was lower than that in the control group(46.67%),and the difference was statistically significant(χ^(2)=9.932,P<0.05).The incidence of adverse pregnancy outcomes such as hemorrhage,postpartum anemia,premature birth,low birth weight infant and neonatal asphyxia in the observation group was 13.33%,which was lower than50.00%in the control group,and the difference was statistically significant(χ^(2)=9.320,P<0.05).Conclusion For preg-nant women,prophylactic iron supplementation under the condition of SF<30μg/L but Hb≥110 g/L can effectively pre-vent the occurrence of anemia during pregnancy and postpartum,and reduce the incidence of adverse pregnancy out-comes.