幽门螺杆菌与结肠息肉的相关性分析

The Correlation Analysis Between Helicobacter Pylori and Colon Polyps

目的分析结肠息肉疾病和机体感染间的相关性。方法方便选取2020年3月—2021年3月山东电力中心医院结肠息肉疾病患者90例纳入分析组,于同时间段内选取健康体检的志愿者90名纳入参照组。两组均采取C尿素呼气检测,对比两组幽门螺杆菌感染情况,并讨论分析组不同病理类型患者的感染率。结果分析组幽门螺杆菌感染率为87.78%,比参照组高,差异有统计学意义(χ^(2)=51.915,P<0.001);分析组有79例患者感染幽门螺杆菌,包括35例腺瘤性息肉患者、17例炎性息肉患者、16例多发息肉患者、11例单发息肉患者,感染率分别为38.89%、18.89%、17.78%及12.22%,病情严重程度与幽门螺杆菌感染情况存在正相关(r=0.76,P<0.001)。结论机体感染幽门螺杆菌后,有较高概率并发结肠息肉疾病,病情越严重,感染幽门螺杆菌的概率越高,因而可知,幽门螺杆菌感染和结肠息肉疾病之间存在密切联系,通过检测幽门螺杆菌感染情况,能够用于评价机体并发结肠息肉及病情进展情况,所以,临床诊断及治疗结肠息肉疾病时,可以通过观察患者感染幽门螺杆菌情况,并结合结肠镜等检查方案进行诊断评估。

Objective To analyze the correlation between colon polyposis disease and infection with Helicobacter pylori.Methods Conveniently selected 90 patients with colonic polyp disease in Shandong Electric Power Central Hospital from March 2020 to March 2021 were included in the analysis group,and 90 volunteers who participated in health examination during the same period were included in the reference group.C-urea breath test was taken in both groups to compare the infection of Helicobacter.pylori in the two groups,and discuss the infection rate of patients with different pathological types in the analysis group.Results The infection rate of Helicobacter.pylori in the analysis group was 87.78%,higher than that in the reference group,the difference was statistically significant(χ^(2)=51.915,P<0.001);in the analysis group,79 patients were infected with Helicobacter pylori,including 35 patients with adenomatous polyp,17 patients with inflammatory polyp,16 patients with multiple polyp,and 11 patients with single polyp,the infection rates were 38.89%,18.89%,17.78%and 12.22%,respectively;there was a positire correlation between the severity of the disease and helicobacter pylori infection(r=0.76,P<0.001).Conclusion After the body is infected with Helicobacter pylori,there is a higher chance of developing colon polyposis.When the disease more is severe,the probability of infection with Helicobacter pylori is higher.Therefore,it can be seen that there is a close relationship between Helicobacter pylori infection and colon polyposis disease.By detecting the infection of Helicobacter pylori,it can be used to evaluate the occurrence of colon polyps and the progress of the disease.Therefore,in the clinical diagnosis and treatment of colon polyposis disease,the diagnosis and evaluation can be carried out by observing the infection of Helicobacter pylori in patients and combining with colonoscopy and other inspection programs.