育龄妇女孕前TORCH血清学抗体筛查的结果分析

Analysis of the results of TORCH serological antibody screening in women of childbearing age before pregnancy

目的探讨TORCH血清学抗体检测在育龄妇女孕前检测的意义。方法回顾性分析2018年1月—2019年12月在天津医科大学第二医院进行孕前TORCH血清学抗体检测的育龄妇女1041例临床资料,对巨细胞病毒(CMV)、弓形虫(TOX)、风疹病毒(RV)和单纯疱疹病毒(HSV)Ⅱ型的IgM和IgG抗体进行检测。分析TORCH检测结果,并比较不同年龄段育龄妇女TORCH血清抗体阳性率。结果1041例进行TORCH血清学抗体筛查中,TOX-IgG、RV-IgG、CMV-IgG和HSV-Ⅱ-IgG阳性率分别为1.83%、87.42%、90.78%和7.88%。TOX-IgM、RV-IgM、CMV-IgM和HSV-Ⅱ-IgM阳性率分别为0.86%、0.38%、1.54%和1.15%。不同年龄段的TORCH血清学IgM和IgG抗体阳性率比较,差异无统计学意义(P>0.05)。结论对育龄妇女进行孕前TORCH血清学抗体筛查,对存在风险的育龄妇女进行干预,有助于降低因TORCH感染导致的不良妊娠结局和出生缺陷风险,为育龄妇女实现优生优育提供帮助。

Objective To explore the significance of TORCH serological antibody screening in women of childbearing age before pregnancy.Methods The clinical data of 1041 women of childbearing age who were tested for TORCH serological antibody before pregnancy in the Second Hospital of Tianjin Medical University from January 2018 to December 2019 were retrospectively analyzed.IgM and IgG antibodies of cytomegalovirus,toxoplasma gondii,rubella virus and herpes simplex virus type Ⅱ were detected.The results of TORCH detection were analyzed and the positive rates of TORCH serum antibody in women of different age groups were compared.Results In 1041 cases of TORCH serological antibody screening,the positive rates of TOX-IgG,RV-IgG,CMV-IgG and HSV-Ⅱ-IgG were 1.83%,87.42%,90.78% and 7.88% respectively;the positive rates of TOX-IgM,RV-IgM,CMV-IgM and HSV-Ⅱ-IgM were 0.86%,0.38%,1.54% and 1.15%,respectively.There was no significant difference in the positive rate of TORCH serological IgM and IgG antibody in different age groups(P>0.05).Conclusion TORCH serological antibody screening for women of childbearing age beforepregnancy and intervention for women of childbearing age at risk would help to reduce the risk of adverse pregnancy outcomes and birth defects caused by TORCH infection,and provide help for women of childbearing age to achieve good childbirth and nurture.