摘要
门静脉血栓(portal vein thrombosis,PVT)是指门静脉主干管腔内血栓形成,可延伸至门静脉左右分支,引起门静脉回流受阻,严重时完全堵塞。在普通人群中,PVT发生少见,约为1%。在肝硬化患者中,尤其是门脉高压患者,PVT是一种常见的并发症,发生率随着门脉高压的进展增加。PVT的进展增加了门脉压力和食管胃静脉曲张的出血风险。阐明PVT在肝硬化进程中的作用及合并食管胃静脉曲张的处理策略,是早期识别PVT的演变、寻找启动治疗的最佳时机、减少患者出血风险、改善患者预后的关键。
Portal vein thrombosis(PVT)refers to the thrombosis in the main lumen of the portal vein,which can extend to the left and right branches of the portal vein,causing the portal vein reflux to be blocked,or even completely blocked in severe cases. In the general population,PVT is rare,about 1%. PVT is a common complication in patients with liver cirrhosis,especially in patients with portal hypertension,and its incidence increases with the progress of portal hypertension. The progress of PVT increases the portal pressure and the risk of bleeding from esophageal and gastric varices.To clarify the role of PVT in the process of liver cirrhosis and the treatment strategy of esophageal and gastric varices is the key to early identify the evolution of PVT,find the best time to start treatment,reduce the risk of bleeding and improve the prognosis of patients.
作者
张瑞
马丽黎
ZHANG Rui;MA Li-li(Department of Gastroenterology,Zhongshan Hospital Fudan University,Shanghai 200032,China)
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2022年第10期820-823,830,共5页
Chinese Journal of Practical Internal Medicine
基金
上海市自然科学基金(21ZR1447600)。
关键词
门静脉血栓
肝硬化
食管胃静脉曲张
portal vein thrombosis
liver cirrhosis
esophageal and gastric varices