囊性中性粒细胞性肉芽肿性乳腺炎的研究进展

Research progress of cystic neutrophilic granulomatous mastitis

肉芽肿性小叶性乳腺炎(granulomatous lobular mastitis,GLM)是一种罕见的乳腺炎性疾病,主要发病于育龄期女性。GLM的病因、诊断和治疗仍存在争议。近年来,棒状杆菌感染在GLM发病中的作用越来越受到关注。自囊性中性粒细胞性肉芽肿性乳腺炎(cystic neutrophilic granulomatous mastitis,CNGM)被提出以来,越来越多的研究将CNGM作为GLM的独特亚型进行针对研究。该文将迄今发表的CNGM相关的文献进行了总结,以论述CNGM的病因、病理、临床表现、辅助检查以及治疗方面的研究进展。

Granulomatous lobular mastitis(GLM)is a rare mastitis disease,which mainly occurs in childbearing period.The etiology,diagnosis and treatment of GLM are still disputed.In recent years,the role of Corynebacterium infection in the pathogenesis of GLM has attracted more and more attention.Cystic neutrophilic granulomatous mastitis(CNGM)has been proposed,and more and more studies have targeted CNGM as a unique subtype of GLM.This article summarizes the published literature on CNGM so far to discuss the research progress in clinicopathological features,microbiological findings,clinical diagnosis and treatment of CNGM.