人参皂苷Rb1抗炎作用及其机制研究进展

Research Progress on Anti-inflammatory Effect and Mechanism of Ginsenoside Rb1

人参皂苷Rb1(GRb1)是一种人参二醇系皂苷单体,具有多种生物学作用。抗炎作用是GRb1最主要的生物学作用之一,在多种疾病的抗感染治疗中备受关注。本文综述了GRb1在心血管、神经、呼吸、消化系统疾病中的抗炎作用及其机制,为深入理解GRb1介导抗炎作用的分子机制提供了新的视角,也为其预防和治疗炎症性疾病提供理论基础。

Ginsenoside Rb1(GRb1)is a panaxadiol saponin monomer,with various biological effects.Antiinflammatory effect is one of the most important biological effects of GRb1,which has attracted the attention of in the anti-inflammatory treatment for various diseases.This article reviews the anti-infective effect and mechanism of GRb1 in cardiovascular,neurological,respiratory,and digestive system diseases,providing a new perspective for in-depth understanding the molecular mechanism of ginsenoside Rb1-mediated anti-inflammatory effects,and also providing a theoretical basis for the prevention and treatment of inflammatory diseases.