心肺复苏基础研究热点与展望

Basic research hotspot and prospect of cardiopulmonary resuscitation

心肺复苏基础研究是现代心肺复苏学的重要组成部分,对于解析心肺复苏相关机制,改进现有心肺复苏策略和发现新的治疗靶点至关重要。本文对复苏时治疗措施(胸外心脏按压、药物治疗)和复苏后治疗措施(目标温度管理和药物治疗)、复苏后脑损伤机制及预后评估等当前心肺复苏基础研究热点做一述评,以期为心肺复苏基础和临床研究提供参考。

Basic research on cardiopulmonary resuscitation(CPR)is an important part of modern CPR,which is of great importance for the analysis of relevant mechanisms,improvement of existing CPR strategies and discovery of new therapeutic targets.This paper mainly reviews the current hot topics in basic research of CPR,such as treatment measures during resuscitation(external cardiac compression,drug therapy),post-resuscitation treatment measures(target temperature management and drug therapy),post-resuscitation brain injury mechanism and prognosis assessment,in order to provide reference for basic and clinical research of cardiopulmonary resuscitation.