1990年与2019年中国归因于饮酒的疾病负担分析

Disease burden attributable to alcohol consumption in China in 1990 and 2019

目的分析1990年与2019年中国归因于饮酒导致的疾病负担。方法采用2019年全球疾病负担数据库,分析我国1990年与2019年归因于饮酒的人群归因分值(PAF)、死亡率、伤残调整寿命年(DALY)等指标及其变化趋势;对比中国与全球及不同社会人口学指数(SDI)地区饮酒导致的疾病负担。结果与1990相比,2019年中国居民归因于饮酒的PAF上升了12.85%,死亡人数增加至51.47万例,死亡率增长至36.18/10万,DALY增加至1726.51万人年,DALY率上升了5.16%。男性归因于饮酒的疾病负担高于女性,70岁以上老年人群归因饮酒导致的死亡率和DALY率高于年轻人群。2019年中国归因于饮酒导致食管癌疾病负担变化最高,其次为结直肠癌。与全球及不同SDI地区相比,中国归因于饮酒的标化DALY率最低。结论饮酒是导致我国相关疾病及癌症的重要危险因素之一,应针对重点人群采取有效的干预措施。

Objective To compare and analyze the disease burden caused by drinking in China in 1990 and 2019.Methods The global disease burden database 2019 was used to analyze the attribution score(PAF),mortality,disability adjusted life year(DALY)and other indicators attributed to drinking in China in 1990 and 2019.The disease burden caused by alcohol consumption was compared between China and the world as well as different social demographic index(SDI)regions.Results From 1990 to 2019,the PAF attributed to drinking increased by 12.85%.The number of deaths attributed to drinking increased to 514700,and the mortality increased to 36.18/100000,while the DALY attributed to drinking increased to 17.2651 million person-years,and the DALY rate increased by 5.16%.The disease burden attributed to drinking was higher in men than that in women,and the attributable mortality and DALY rate in the elderly over 70 years old were higher than those in the young.From 1990 to 2019,the attributable disease burden of esophageal cancer was the highest in China,followed by colorectal cancer.Compared with the world and different SDI regions,China had the lowest standardized DALY rate attributed to drinking.Conclusion Drinking is one of the important risk factors for related diseases and cancers in China,and effective intervention measures should be taken for key populations.