中药镇痛膏外用治疗癌性疼痛的临床效果观察

Observation of Clinical Effect of External Application of Traditional Chinese Medicine Analgesia Ointment in Treatment of Cancer Pain

目的:探讨中药镇痛膏外用治疗癌性疼痛的临床效果。方法:选取2019年1月-2021年12月铜陵市立医院收治的46例癌性疼痛患者为研究对象,通过计算机软件分为参照组和治疗组,各23例。两组均接受三阶梯疼痛治疗,在此基础上,参照组接受安慰剂外敷,治疗组接受中药镇痛膏外用,比较两组疼痛缓解率、疼痛暴发次数、吗啡消耗总量、吗啡首日消耗量、生活质量评分及不良反应发生率。结果:治疗组疼痛缓解率高于参照组,差异有统计学意义(P<0.05)。治疗组疼痛暴发次数、吗啡消耗总量以及吗啡首日消耗量均少于参照组,差异有统计学意义(P<0.05)。治疗前,两组心理、生理、环境、社会评分比较,差异无统计学意义(P>0.05);治疗后,治疗组心理、生理、环境、社会评分均高于参照组,差异有统计学意义(P<0.05)。治疗组不良反应发生率低于参照组,差异有统计学意义(P<0.05)。结论:中药镇痛膏外用治疗癌性疼痛的效果显著,可缓解患者的疼痛程度,提高患者生活质量,安全性高。

Objective: To investigate the clinical effect of external application of traditional Chinese medicine analgesia ointment in the treatment of cancer pain. Methods: A total of 46 patients with cancer pain who were admitted to Tongling Municipal Hospital from January 2019 to December 2021 were selected as the study subjects. They were divided into a reference group and a treatment group by computer software, with 23 cases in each group. Both groups received three-step pain treatment. On this basis,the reference group was given external application of placebo, and the treatment group was given external application of traditional Chinese medicine analgesic ointment. The pain relief rate, number of pain outbreaks, total morphine consumption, morphine consumption on the first day, quality of life score and incidence of adverse reactions were compared between the two groups. Results:The pain relief rate in the treatment group was higher than that in the reference group, and the difference was statistically significant(P<0.05). The number of pain outbreaks, total morphine consumption and morphine consumption on the first day in the treatment group were less than those in the reference group, and the difference was statistically significant(P<0.05). Before treatment, there was no statistically significant difference in the psychological, physiological, environmental and social scores between the two groups(P>0.05). After treatment, the psychological, physiological, environmental and social scores in the treatment group were higher than those in the reference group, and the differences were statistically significant(P<0.05). The incidence of adverse reactions in the treatment group was lower than that in the reference group, and the difference was statistically significant(P<0.05). Conclusion: The external application of traditional Chinese medicine analgesia ointment in the treatment of cancer pain has significant effects, it can relieve the pain degree of patients, improve the quality of life of patients, and has high safety.