西药房高危药品管理与使用研究

Management and use of high-risk drugs in western medicine pharmacies

高危药品药效强烈, 使用不当可对机体产生严重损害或依赖性, 后果严重。高危药品的管理和使用是临床药品安全管理的重要内容, 西药房是药品管理和使用的核心部门和重要一环。笔者对国内外关于临床高危药物的管理和使用的文献进行综述, 了解目前存在的主要问题以及主要影响因素, 分析关于高危药品管理和使用的主要干预措施, 以提高临床和药房对高危药品的重视程度和规范科学使用, 避免因管理和使用不当导致医疗事故的发生, 并提出相应的管理策略, 进一步规范高危药品管理和使用。

High-risk drugs have strong efficacy and can cause remarkable patient harm or drug dependence,leading to serious consequences,when they are used in error.Management and use of high-risk drugs is an important part of clinical drug safety management.Western medicine pharmacy is the core department and an important link of drug management and use.We reviewed the literature on the management and use of clinical high-risk drugs at home and abroad,investigated the current main problems and influential factors,analyzed the main intervention measures on the management and use of high-risk drugs,so as to increase physician's and pharmacy's attention to high-risk drugs,standardize scientific use,and avoid medical accidents due to improper management and use of high-risk drugs.All of these will help us to put forward corresponding management strategies and further standardize the management and use of high-risk drugs.